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Beyond library size: a field guide to NGS normalization

bioRxiv

Jun 19, 2014

Jelena AleksicMichaela Frye

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Abstract

Background: Next generation sequencing (NGS) is a widely used technology in both basic research and clinical settings and it will continue to have a major impact on biomedical sciences. However, the use of incorrect normalization methods can lead to systematic biases and spurious result...read more

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Silo (Dataset)
Biomedicine
Massively-Parallel Sequencing
49
2
150
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  • Beyond library size: a field guide to NGS normalization

    bioRxiv

    Jun 19, 2014

    Jelena AleksicMichaela Frye

    PMID: 990006403

    DOI: 10.1101/006403

    Abstract

    Background: Next generation sequencing (NGS) is a widely used technology in both basic research and clinical settings and it will continue to have a major impact on biomedical sciences. However, the use of incorrect normalization methods can lead to systematic biases and spurious result...read more

    Mentioned in this Paper

    Silo (Dataset)
    Biomedicine
    Massively-Parallel Sequencing
    49
    2
    150

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