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Beyond library size: a field guide to NGS normalization

bioRxiv

Jun 19, 2014

Jelena AleksicMichaela Frye

Abstract

Background: Next generation sequencing (NGS) is a widely used technology in both basic research and clinical settings and it will continue to have a major impact on biomedical sciences. However, the use of incorrect normalization methods can lead to systematic biases and spurious result...read more

Mentioned in this Paper

Study
Basic Research
Size
Genes
Chromatin Immunoprecipitation
TAPBP protein, human
Normalize
Massively-Parallel Sequencing
Downstream
Analysis
49
2
157
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Beyond library size: a field guide to NGS normalization

bioRxiv

Jun 19, 2014

Jelena AleksicMichaela Frye

PMID: 990006403

DOI: 10.1101/006403

Abstract

Background: Next generation sequencing (NGS) is a widely used technology in both basic research and clinical settings and it will continue to have a major impact on biomedical sciences. However, the use of incorrect normalization methods can lead to systematic biases and spurious result...read more

Mentioned in this Paper

Study
Basic Research
Size
Genes
Chromatin Immunoprecipitation
TAPBP protein, human
Normalize
Massively-Parallel Sequencing
Downstream
Analysis
49
2
157

Related Papers

Paper Details
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