Bgp, a secreted glycosaminoglycan-binding protein of Borrelia burgdorferi strain N40, displays nucleosidase activity and is not essential for infection of immunodeficient mice.

Infection and Immunity
Nikhat ParveenJohn M Leong

Abstract

Bgp, one of the surface-localized glycosaminoglycan-binding proteins of the Lyme disease spirochete, Borrelia burgdorferi, exhibited nucleosidase activity. Infection of SCID mice with B. burgdorferi strain N40 mutants harboring a targeted insertion in bgp and apparently retaining all endogenous plasmids revealed that Bgp is not essential for colonization of immunocompromised mice.

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Citations

Jul 24, 2013·Trends in Microbiology·Jenifer CoburnGeorge Chaconas
Sep 17, 2009·The Journal of Infectious Diseases·Erol FikrigRichard Flavell
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