Abstract
The purpose of this study was to measure the sodium transverse relaxation time T2 * in the healthy human brain. Five healthy subjects were scanned with 18 echo times (TEs) as short as 0.17 ms. T2 * values were fitted on a voxel-by-voxel basis using a bi-exponential model. Data were also analysed using a continuous distribution fit with a region of interest-based inverse Laplace transform. Average T2 * values were 3.4 ± 0.2 ms and 23.5 ± 1.8 ms in white matter (WM) for the short and long components, respectively, and 3.9 ± 0.5 ms and 26.3 ± 2.6 ms in grey matter (GM) for the short and long components, respectively, using the bi-exponential model. Continuous distribution fits yielded results of 3.1 ± 0.3 ms and 18.8 ± 3.2 ms in WM for the short and long components, respectively, and 2.9 ± 0.4 ms and 17.2 ± 2 ms in GM for the short and long components, respectively. 23 Na T2 * values of the brain for the short and long components for various anatomical locations using ultra-short TEs are presented for the first time.
References
Aug 1, 1991·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R S Menon, P S Allen
Jun 1, 1994·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·A MacKayD Graeb
Jan 1, 1993·Magnetic Resonance Imaging·A J Miller, P M Joseph
Jul 30, 2004·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Robert Bartha, Ravi S Menon
Mar 16, 2006·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jürgen RahmerClemens Bos
Feb 14, 2009·AJNR. American Journal of Neuroradiology·E A MellonR Reddy
Sep 26, 2009·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Lazar FleysherMatilde Inglese
Jan 30, 2010·Brain : a Journal of Neurology·M IngleseG Johnson
Aug 20, 2011·NMR in Biomedicine·Guillaume MadelinRavinder R Regatte
Jun 21, 2012·NMR in Biomedicine·Lazar FleysherMatilde Inglese
Jul 17, 2012·NeuroImage·Kathrin ReetzN Jon Shah
Jul 19, 2012·Radiology·Wafaa ZaaraouiJean-Philippe Ranjeva
Jun 1, 2013·Journal of Magnetic Resonance Imaging : JMRI·Guillaume Madelin, Ravinder R Regatte
Jun 27, 2013·Brain : a Journal of Neurology·David PalingDavid H Miller
Aug 3, 2013·Magma·Adil MaaroufWafaa Zaaraoui
Feb 18, 2014·Journal of Magnetic Resonance·Nadia BenkhedahArmin M Nagel
Apr 24, 2014·Scientific Reports·Guillaume MadelinRavinder R Regatte
Mar 18, 2017·Journal of Magnetic Resonance·Victor D SchepkinThomas F Budinger
Citations
Jan 18, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Warda SyedaLeigh A Johnston
Dec 17, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·James T GristChristoffer Laustsen
Jun 2, 2020·Journal of Magnetic Resonance Imaging : JMRI·Bhavana S SolankyClaudia A M Gandini Wheeler-Kingshott
Nov 10, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Ahmad A AlhulailUzay E Emir
Jul 17, 2021·Magnetic Resonance Imaging·Mark BydderBenjamin M Ellingson
Oct 16, 2021·NMR in Biomedicine·Paul PolakMichael D Noseworthy