Bi-level positive airway pressure ventilation maintains adequate ventilation in post-polio patients with respiratory failure

Acta Anaesthesiologica Scandinavica
C Gillis-HaegerstrandH Barle

Abstract

Patients suffering from post-polio syndrome still contribute significantly to the number of patients with chronic respiratory failure requiring home mechanical ventilation (HMV). Many of these patients are treated either with invasive (tracheostomy) or non-invasive (nasal mask) controlled mechanical ventilation i.e. volume-controlled ventilation (VCV). In this group of patients, we have previously shown that bi-level pressure support ventilation (bi-level PSV) decreases the oxygen cost of breathing. The aim of this study was to compare the effect of bi-level PSV, with special regard to the adequacy of ventilation and the oxygen cost of breathing, during the patients' ordinary VCV and spontaneous breathing. Eight post-polio patients on nocturnal VCV were investigated. Five of them were tracheostomized and three of them used a nasal mask. Work of breathing was analysed by assessing differences in oxygen consumption (VO2) using indirect calorimetry. Blood gases were obtained regularly to assess adequacy of ventilation. Bi-level PSV decreases the oxygen cost of breathing in post-polio patients with respiratory failure without decreasing ventilation efficiency. Furthermore, PaCO2 decreased significantly using this mode of ventilatio...Continue Reading

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Citations

Dec 1, 2009·Annals of Physical and Rehabilitation Medicine·I LaffontJ Pelissier
Aug 6, 2019·Frontiers in Neurology·Stacey Li Hi ShingPeter Bede
Oct 2, 2012·Neurologia i neurochirurgia polska·Ewa Matyja
Dec 4, 2019·Annals of Physical and Rehabilitation Medicine·Antoine LéotardMaria Antonia Quera-Salva

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