Biaxial incremental homeostatic elastic moduli of coronary artery: two-layer model

American Journal of Physiology. Heart and Circulatory Physiology
Xiao LuGhassan S Kassab

Abstract

The detailed mechanical properties of various layers of the coronary artery are important for understanding the function of the vessel. The present article is focused on the determination of the incremental modulus in different layers and directions in the neighborhood of the in vivo state. The incremental modulus can be defined for any material subjected to a large deformation if small perturbations in strain lead to small perturbations of stresses in a linear fashion. This analysis was applied to the porcine coronary artery, which was treated as a two-layered structure consisting of an inner intima-media layer and an outer adventitia layer. We adopted a theory based on small-perturbation experiments at homeostatic conditions for determination of incremental moduli in circumferential, axial, and cross directions in the two layers. The experiments were based on inflation and axial stretch. We demonstrate that under homeostatic conditions the incremental moduli are layer- and direction dependent. The incremental modulus is highest in the circumferential direction. Furthermore, in the circumferential direction, the media is stiffer than the whole wall, which is stiffer than the adventitia. In the axial direction, the adventitia i...Continue Reading

References

Feb 1, 1992·The American Journal of Physiology·Y C Fung, S Q Liu
Jan 1, 1991·Annals of Biomedical Engineering·Y C Fung
Jul 1, 1968·Circulation Research·B S Gow, M G Taylor
Mar 1, 1966·Circulation Research·B M Learoyd, M G Taylor
Jan 1, 1981·Journal of Biomechanics·W W von MaltzahnW Wiemer
May 1, 1995·Journal of the American Geriatrics Society·R J HodesC T McNeil
Mar 14, 1995·Proceedings of the National Academy of Sciences of the United States of America·Y C Fung, S Q Liu
Oct 15, 1994·American Journal of Epidemiology·D K ArnettW A Riley
Jan 1, 1995·Advances in Experimental Medicine and Biology·R Hainsworth
Apr 5, 2003·Stroke; a Journal of Cerebral Circulation·Stéphane LaurentPierre Boutouyrie
May 2, 2003·Annals of Biomedical Engineering·Hai-Chao HanRaymond P Vito
May 1, 1962·Circulation Research·J C GREENFIELD, D J PATEL
Oct 17, 2003·American Journal of Physiology. Heart and Circulatory Physiology·X LuG S Kassab

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Citations

Sep 26, 2008·Tissue Engineering. Part a·Cathy ChuMarie-Claude Hofmann
Jul 13, 2011·Journal of Biomechanical Engineering·Yaniv HollanderYoram Lanir
Mar 20, 2012·American Journal of Physiology. Heart and Circulatory Physiology·Yunlong HuoGhassan S Kassab
Jan 31, 2009·Journal of Applied Physiology·Marisa Garcia, Ghassan S Kassab
Aug 7, 2010·International Journal of Biomaterials·John C FitzpatrickFranco M Capaldi
Mar 9, 2013·Journal of Applied Physiology·Yunlong HuoGhassan S Kassab
May 1, 2015·Frontiers in Genetics·Julie C KohnCynthia A Reinhart-King
Mar 29, 2005·American Journal of Physiology. Heart and Circulatory Physiology·Aditya PanditGhassan S Kassab
Feb 27, 2008·Journal of Biomechanical Engineering·Hans GregersenYuan Cheng Fung
Mar 12, 2009·Journal of Biomechanical Engineering·Yoram Lanir
Aug 14, 2009·Clinical and Experimental Pharmacology & Physiology·Wei-Qing HanPing-Jin Gao
Apr 30, 2009·Journal of Biomedical Materials Research. Part a·Dany J Munoz-PintoMariah S Hahn
Jul 12, 2005·American Journal of Physiology. Heart and Circulatory Physiology·Gerhard A HolzapfelPeter Regitnig
Jun 18, 2010·Biomechanics and Modeling in Mechanobiology·Chantal N van den BroekFrans N van de Vosse
Apr 12, 2014·Biomechanics and Modeling in Mechanobiology·Dibyendu SenguptaAlison L Marsden
Jul 23, 2014·Cardiovascular Engineering and Technology·Ethan KungAlison Marsden
Apr 4, 2006·American Journal of Physiology. Heart and Circulatory Physiology·Chong WangGhassan S Kassab
May 26, 2007·Journal of Applied Physiology·Wei ZhangGhassan S Kassab
Oct 5, 2013·Journal of Applied Physiology·Huan ChenGhassan S Kassab
May 11, 2019·Journal of Biomechanical Engineering·Parastou EslamiAlison Marsden
Oct 19, 2019·Cardiovascular Engineering and Technology·Keiichi Takamizawa
Jul 3, 2019·Interface Focus·Gabrielle L ClarkKristin S Miller
Jan 15, 2005·American Journal of Physiology. Heart and Circulatory Physiology·Xiaomei GuoGhassan S Kassab
Dec 29, 2020·Journal of the Mechanical Behavior of Biomedical Materials·Robin TrostorfMarkus Böl
Dec 24, 2019·The American Journal of Pathology·Maria G Tinajero, Avrum I Gotlieb
Oct 9, 2021·Biomechanics and Modeling in Mechanobiology·Keiichi Takamizawa

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