Bicuspid valve-related aortic disease: flow assessment with conventional phase-contrast MRI

Academic Radiology
Nicholas S Burris, Michael D Hope

Abstract

Abnormal blood flow with bicuspid aortic valve (BAV) has been characterized with four-dimensional flow magnetic resonance imaging (MRI), but this approach is time consuming and requires technical expertise. We assess the relationship between different leaflets fusion patterns with BAV, eccentric systolic flow, and dilation patterns of the ascending aorta using two-dimensional (2D) phase-contrast (PC) MRI. Fifty-nine patients with BAV who underwent cardiac MRI were identified; 47 had right-left (RL) aortic leaflet fusion and 12 had right-noncoronary (RN) fusion. Flow displacement was calculated, and patients with abnormal displacement (>0.1) were classified as either rightward or leftward. Patterns of aortopathy were determined (0-3), and correlation between leaflet fusion, flow direction, aortopathy type, and other clinical parameters was performed with Pearson correlation, the Fisher exact test and chi-square analysis. Normal systolic flow was seen in 24% of cases and was significantly correlated with normal aortas (P = .011). Abnormal flow displacement with RL fusion was strongly associated with rightward deviation (36 of 37 cases), whereas RN fusion skewed leftward (seven of eight cases; P < .01). In patients with aortopathy...Continue Reading

Citations

Apr 9, 2017·Journal of Magnetic Resonance Imaging : JMRI·Vrishank RaghavAjit P Yoganathan
Sep 6, 2017·The International Journal of Cardiovascular Imaging·Odd Bech-HanssenKerstin M Lagerstrand
Jan 12, 2019·Current Opinion in Cardiology·Ali Fatehi HassanabadPaul W M Fedak
Feb 11, 2018·Scientific Reports·Hanna M BjörckUNKNOWN Mechanistic Interrogation of Bicuspid Aortic Valve associated Aortopathy (MIBAVA) Leducq Consortium
Sep 22, 2018·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Joy EdlinMarjan Jahangiri
Jan 11, 2020·Frontiers in Cardiovascular Medicine·Shohreh MalekiPer Eriksson
Oct 23, 2019·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Omar A JarralThanos Athanasiou
Jul 13, 2019·Current Problems in Cardiology·Alessandro Della CorteAmalia Forte
Nov 20, 2016·Journal of Biomechanics·Kai CaoPhilippe Sucosky

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