Big data and analysis of risk factors for gallbladder disease in the young generation of Korea

PloS One
Hyung Sun KimJoon Seong Park

Abstract

Few studies have examined the risk factors for gallbladder (GB) disease in young adults. This study aimed to evaluate risk factors for GB disease in young adults based on big data in Korea. All participants underwent routine checkup at the Korea Medical Institute from June 2014 to May 2015. After excluding 677 individuals with missing information in records, 724,114 individuals (435,635 men, 288,479 women) were finally included. The definition of abnormal GB finding included stones, sludge, polyps, and adenomyomatosis detected using ultrasonography. All statistical analyses were performed using SAS software version 9.2. Overall, 27,130 (17.5%) individuals were diagnosed as having abnormal GB finding in the young age group (N = 154,463, aged 20-39 years). In men, significant differences in low-density lipoprotein (LDL) and cholesterol levels were observed between the abnormal GB finding group and normal GB group (p < 0.05). In women, a significant difference in smoking history was noted between the abnormal GB finding group and normal GB group (p < 0.05). The prevalence rate of GB stones was 1.9% (27,979/154,463) in the young age group. High body mass index (BMI), large thigh circumference, and low high-density lipoprotein (HDL)...Continue Reading

References

Mar 25, 1989·BMJ : British Medical Journal·W Y CraigJ E Haddow
Sep 1, 1988·American Journal of Epidemiology·H NomuraM Goto
Aug 1, 1993·Journal of the American College of Cardiology·E D Frohlich
Sep 9, 1999·The New England Journal of Medicine·M F LeitzmannE Giovannucci
May 23, 2001·JAMA : the Journal of the American Medical Association·UNKNOWN Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
Oct 12, 2004·Clinics in Dermatology·Philip T James
Jul 18, 2006·Lancet·Piero PortincasaGiuseppe Palasciano
Sep 21, 2006·Journal of Gastroenterology and Hepatology·Chien-Hua ChenSen-Kou Yueh
Sep 29, 2006·World Journal of Gastroenterology : WJG·Bumin DegirmenciAylin Yucel
Dec 25, 2007·Annals of Surgery·Chung-Jyi TsaiEdward L Giovannucci
Apr 17, 2009·World Journal of Gastroenterology : WJG·Hui SunYou-Juan Wang
Sep 28, 2010·Journal of Obesity·Ambady Ramachandran, Chamukuttan Snehalatha
Jan 19, 2011·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Sayeed UnisaTarun Kumar Roy
Mar 1, 2011·Clinics and Research in Hepatology and Gastroenterology·Karel Johannes Van Erpecum
Aug 28, 2013·Reviews in Endocrine & Metabolic Disorders·Miguel Ángel Martínez-González, Nerea Martín-Calvo
Mar 15, 2014·Diabetes & Metabolism Journal·Chul Sik KimUNKNOWN Taskforce Team of Diabetes Fact Sheet of the Korean Diabetes Association
Dec 17, 2014·Laboratory Investigation; a Journal of Technical Methods and Pathology·Yongsheng ChenShuodong Wu
Jan 1, 2014·Health Psychology and Behavioral Medicine·Amudha S PoobalanWilliam Cairns S Smith
Sep 17, 2015·European Journal of Epidemiology·Dagfinn AuneLars J Vatten
Feb 24, 2016·European Journal of Epidemiology·Dagfinn AunePaolo Boffetta
Apr 18, 2016·Journal of Hepatology·UNKNOWN European Association for the Study of the Liver (EASL). Electronic address: easloffice@easloffice.eu
Apr 29, 2016·Nature Reviews. Disease Primers·Frank LammertDavid Q-H Wang
Jun 9, 2016·JAMA : the Journal of the American Medical Association·Cynthia L OgdenKatherine M Flegal
Sep 10, 2016·Scandinavian Journal of Gastroenterology·Jian-Shan CaiYin Bao-Bing
Nov 22, 2016·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Susanna C LarssonAlicja Wolk
Mar 9, 2017·European Journal of Clinical Nutrition·T J McConnellT J Key
May 26, 2018·European Journal of Clinical Investigation·Emilio Molina-MolinaPiero Portincasa

❮ Previous
Next ❯

Citations

Mar 18, 2021·Zeitschrift für Gastroenterologie·Wolfgang KratzerUNKNOWN EMIL-Study group
May 22, 2021·Mycotoxin Research·Jéssica CostaCledir Santos
Nov 2, 2021·Visceral Medicine·Nela Melissa Parra-LandazuryNahum Méndez-Sánchez

❮ Previous
Next ❯

Software Mentioned

SAS

Related Concepts

Related Feeds

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.