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Big renin and biosynthetic defect of aldosterone in diabetes mellitus

The New England Journal of Medicine

Sep 16, 1976

A deLeivaPhilip G Zager

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Abstract

To determine the cause of selective aldosterone deficiency in two patients with diabetes mellitus, studies of renin and of aldosterone-precursor metabolites were performed under conditions of sodium depletion and ACTH stimulation. Plasma renin concentration was elevated in both patients...read more

Mentioned in this Paper

Potassium
Corticotropin
Thyroid Hormone Plasma Membrane Transport Defect
Plasma Renin Measurement
Renin Measurement
Hyperkalemia
Corticosterone 18-monooxygenase
Sodium
POMC gene
Steroid Hydroxylases
Paper Details
References
  • References39
  • Citations38
1234
  • References39
  • Citations38
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Big renin and biosynthetic defect of aldosterone in diabetes mellitus

The New England Journal of Medicine

Sep 16, 1976

A deLeivaPhilip G Zager

PMID: 184384

DOI: 10.1056/nejm197609162951203

Abstract

To determine the cause of selective aldosterone deficiency in two patients with diabetes mellitus, studies of renin and of aldosterone-precursor metabolites were performed under conditions of sodium depletion and ACTH stimulation. Plasma renin concentration was elevated in both patients...read more

Mentioned in this Paper

Potassium
Corticotropin
Thyroid Hormone Plasma Membrane Transport Defect
Plasma Renin Measurement
Renin Measurement
Paper Details
References
  • References39
  • Citations38
1234
  • References39
  • Citations38
1234

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