Bihippocampal damage with emotional dysfunction: impaired auditory recognition of fear

European Neurology
F Ghika-SchmidJ Bogousslavsky

Abstract

A right-handed man developed a sudden transient, amnestic syndrome associated with bilateral hemorrhage of the hippocampi, probably due to Urbach-Wiethe disease. In the 3rd month, despite significant hippocampal structural damage on imaging, only a milder degree of retrograde and anterograde amnesia persisted on detailed neuropsychological examination. On systematic testing of recognition of facial and vocal expression of emotion, we found an impairment of the vocal perception of fear, but not that of other emotions, such as joy, sadness and anger. Such selective impairment of fear perception was not present in the recognition of facial expression of emotion. Thus emotional perception varies according to the different aspects of emotions and the different modality of presentation (faces versus voices). This is consistent with the idea that there may be multiple emotion systems. The study of emotional perception in this unique case of bilateral involvement of hippocampus suggests that this structure may play a critical role in the recognition of fear in vocal expression, possibly dissociated from that of other emotions and from that of fear in facial expression. In regard of recent data suggesting that the amygdala is playing a ...Continue Reading

Citations

Jan 17, 2004·Magnetic Resonance Imaging·Francesco Di SalleErich Seifritz
Aug 14, 2002·Applied Neuropsychology·Joan C BorodElizabeth A Curko
Aug 20, 2002·Memory & Cognition·Lynne C Nygaard, Erin R Lunders
Nov 5, 2002·Psychonomic Bulletin & Review·Alan S Brown
Apr 20, 2004·Current Opinion in Neurology·Benedetta BodiniGian Luigi Lenzi
Nov 9, 2016·Journal of the Neurological Sciences·Emre Kumral, Oral Zirek
Jun 20, 2006·Neuroscience and Behavioral Physiology·M I Zaichenko, N G Mikhailova

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