Bilateral carotid artery occlusion with transient or moderately disabling ischaemic stroke: clinical features and long-term outcome

Journal of Neurology
Suzanne PersoonL J Kappelle

Abstract

Information on the prognosis of patients with transient ischaemic attack or moderately disabling ischaemic stroke associated with bilateral internal carotid artery (ICA) occlusion is scarce. We prospectively studied 57 consecutive patients (46 men; mean age 60 +/- 9 years) with bilateral ICA occlusion who had presented with unilateral transient or moderately disabling cerebral or retinal ischaemic symptoms. We determined the long-term risk of recurrent ischaemic stroke and the composite outcome of stroke, myocardial infarction or vascular death. Four patients had a recurrent ischaemic stroke during a mean follow-up of 5.9 years, resulting in an annual stroke rate of 1.2% (95% confidence interval (CI) 0.3-3.1). Risk factors for recurrent ischaemic stroke could not be identified. Eighteen patients suffered a stroke, myocardial infarction or vascular death, resulting in an annual rate for major vascular events of 5.3% (95% CI 3.1-8.3). Age and a history of ischaemic heart disease were significant risk factors for future vascular events. Patients with transient or moderately disabling symptoms of cerebral or retinal ischaemia associated with bilateral ICA occlusion have a relatively low risk of recurrent ischaemic stroke. Although ...Continue Reading

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Nov 30, 2010·Journal of Neurology·Mirta López, Antoni Dávalos
Jul 4, 2012·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Luca Peruzzotti-JamettiMaria Sessa
Jun 21, 2015·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Zhilin XiongLi'an Huang
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Related Concepts

Brain
Internal Carotid Artery Diseases
Cerebral Angiography
Brain Ischemia
Crescendo Transient Ischemic Attacks
Relapse
Retinal Diseases
Acute Cerebrovascular Accidents
Brain
Internal Carotid Artery Structure

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