Bilateral Conjunctival Granulomas in A Young Lady with Hypereosinophilic Syndrome - A Case Report

Ocular Immunology and Inflammation
Kalpana BabuS Krishna Kumar

Abstract

To report an interesting case of bilateral conjunctival granulomas in a young lady with hypereosiniophilic syndrome. Retrospective interventional case report Results: A 37-year-old lady presented with irritation and redness in both eyes of 15-day duration. She had a history of abdominal pain and diarrhea since 8 months for which she has been extensively investigated including a positron emission tomography (PET) scan and an ileal biopsy which showed chronic granulomatous inflammation with eosinophils. Ocular examination revealed multiple bilateral conjunctival granulomas. Conjunctival biopsies revealed granulomatous inflammation with plenty of eosinophils and flame figure configuration. Peripheral blood smear showed increased absolute eosinophil count and eosinophilia. Stool analysis was normal. She did not have abdominal symptoms or recurrence of granulomas. The rare association of bilateral conjunctival granulomas with hypereosinophilic syndrome has been described in this report.

References

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Jul 23, 2005·The Kaohsiung Journal of Medical Sciences·Jiunn-Liang ChenTzy-Ing Yeh
Jan 18, 2006·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Ingo SchmackScott R Lambert
Jul 29, 2010·Ocular Immunology and Inflammation·James T RosenbaumDavid J Wilson
May 15, 2013·Ocular Immunology and Inflammation·Bita ManzouriJimmy Uddin
Feb 14, 2015·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Eric FeinsteinAisha S Traish
Oct 11, 2016·Survey of Ophthalmology·Tapas Ranjan PadhiCagri G Besirli

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