PMID: 6107141Apr 1, 1980Paper

Bilateral germ cell tumours of the testis

British Journal of Urology
M SokalW F Hendry

Abstract

Between 1952 and 1976, 760 men with testicular tumours were seen at The Royal Marsden Hospital. Of this group 21 (2.75%) developed tumours of the contralateral testis, in 2 instances synchronously and in the remaining 19 at intervals from 4 months to 15 years. Of 15 men in whom adequate history has been obtained, 7 (46%) had a history of maldescent and in all 7 patients the pathology of both tumours showed the same histological subtype. Only one example of malignant teratoma undifferentiated (MTU) as first tumour was encountered; 13 of 19 (68%) patients had seminomas and the second tumour was a seminoma in 11 patients (58%). Of the group of 21 patients, 12 (57%) are alive and disease-free. Of 14 Stage I patients (second tumour), 12 (85%) are considered cured of their 2 tumours. However, patients with evidence of extratesticular spread did badly, even if the second tumour was a seminoma, and treatment for these patients should include chemotherapy. Similarly, both Stage I MTU second tumours did badly.

References

Jan 1, 1979·Virchows Archiv. A, Pathological Anatomy and Histology·D Bernhardt-HuthH W Schlösser
Apr 1, 1979·British Journal of Urology·F M CalmanW F Hendry
Feb 1, 1976·Journal of Clinical Pathology·T G Allen-Mersh
Jan 1, 1957·The British Journal of Radiology·R J WHITTLE
Apr 1, 1960·American Journal of Surgery·J F PATTONR A ZONE

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Citations

Jan 1, 1995·International Urology and Nephrology·I CelebiD Remzi
May 1, 1995·Cancer Genetics and Cytogenetics·A M VénuatA Bernheim
Dec 16, 1998·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·D J SonneveldH J Hoekstra
Jul 31, 2004·Urologic Oncology·Hani H RashidEdward M Messing
May 16, 2002·International Journal of Urology : Official Journal of the Japanese Urological Association·Chikara OhyamaSeiichi Orikasa
Apr 1, 1979·British Journal of Urology·F M CalmanW F Hendry
Mar 1, 1990·British Journal of Urology·M V FordhamA Horwich
Aug 1, 1983·The Journal of School Health·P J Marty, R J McDermott
Jun 1, 1997·Annals of Surgical Oncology·J P van BastenH Schraffordt Koops
Feb 1, 1986·British Journal of Urology·S KristianslundK Kjellevold
Feb 1, 1987·International Journal of Andrology·A OsterlindL H Rasmussen
Sep 1, 1991·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·C GlanzmannU M Lütolf
Dec 1, 1994·The Australian and New Zealand Journal of Surgery·S D MarkB M Fitzharris
Mar 1, 1991·The Australian and New Zealand Journal of Surgery·G J Lindeman, K W Tiver
Dec 1, 1984·International Journal of Andrology·J G Berthelsen
Sep 1, 1989·Bulletin of Environmental Contamination and Toxicology·G A LaBarge, R J Kremer
May 1, 1988·The Journal of Pathology·C K Anderson
Apr 1, 1983·European Journal of Clinical Microbiology·H LodeP Koeppe
Jan 1, 1988·Acta Oncologica·M Peckham
Jul 1, 1987·The Journal of Urology·K ScheiberU E Studer
Apr 1, 1985·The Journal of Urology·B J MilesW D Belville

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