Bilateral infiltrative disease of the extraocular muscles: a rare clinical presentation of early stage chronic lymphocytic leukemia

Orbit
Yashin D RamkissoonMike J Potts

Abstract

Orbital involvement in chronic lymphocytic leukemia (CLL) is highly unusual and most commonly involves hemorrhage or soft tissue infiltration in advanced disease. We report a case of rapid onset bilateral orbital muscle infiltration as the presenting feature of early stage CLL. In addition, we demonstrate clinico-pathological correlation with an identical chronic B-cell lymphocytic infiltrate in both orbit and bone marrow, with good response of the orbital disease to local radiotherapy.

References

Aug 1, 1983·Ophthalmology·A R Rosenthal
Jan 1, 1983·Survey of Ophthalmology·M C Kincaid, W R Green
Feb 29, 2000·Eye·S KamalarajahP B Johnston
Jan 10, 2002·Clinical & Experimental Ophthalmology·P A McKelvieJ O'Day

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Citations

Aug 26, 2009·Clinical & Experimental Ophthalmology·Hayyam KiratliAyşegül Uner
Sep 27, 2014·Skeletal Radiology·Alexey SurovRolf Peter Spielmann
Jul 19, 2016·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·Deepesh LadSubhash Varma

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