Bilateral medial medullary infarction: magnetic resonance imaging and correlative histopathologic findings

European Neurology
G KleinertH Lechner

Abstract

Bilateral medial medullary infarction is a rare event which clinically presents with flaccid tetraplegia sparing the face, bilateral disturbance of deep sensation, hypoglossal nerve palsy and respiratory failure. We here report a patient with such symptoms in whom magnetic resonance imaging enabled the detection of signal abnormalities in the lower brainstem as soon as 9 h after onset. Results of a control study 3 weeks later correlated well with the extent of infarction that was seen at autopsy. Early lesion detection in the lower medulla by magnetic resonance imaging and the unfavorable prognosis of patients with ischemic damage at that location may provide the rationale for aggressive therapeutic strategies in such a condition.

Citations

Mar 1, 1995·Journal of Neurology·R Gan, A Noronha
Jan 5, 2002·Neurologia Medico-chirurgica·S OyaT Inoue
Jul 18, 2008·Journal of Perinatology : Official Journal of the California Perinatal Association·A JanvierK J Barrington
Apr 19, 2015·Journal of the Neurological Sciences·Mayra MontalvoMuhib Khan
May 1, 2012·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Jitphapa PongmoragotGustavo Saposnik
Aug 21, 2015·Rinshō shinkeigaku = Clinical neurology·Takayoshi AkimotoSatoshi Kamei
Oct 13, 2000·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·M Katoh, T Kawamoto
Sep 27, 2007·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Y KinoshitaT Terashita
Sep 1, 1995·Stroke; a Journal of Cerebral Circulation·J S KimC S Chung
Nov 8, 2013·Case Reports in Neurological Medicine·Amir M Torabi
Apr 1, 1997·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·T T BatchelorL M DeAngelis
Oct 1, 1996·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·T T BatchelorL M DeAngelis

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