Bilateral or unilateral antegrade cerebral perfusion during surgery for acute type A dissection

The Journal of Thoracic and Cardiovascular Surgery
Philipp AngleitnerMarek Ehrlich

Abstract

The study objective was to investigate outcomes associated with the application of bilateral or unilateral antegrade cerebral perfusion during surgery for acute type A dissection. Patients who underwent surgery for type A dissection with the application of antegrade cerebral perfusion between 2009 and 2017 at the Division of Cardiac Surgery, Medical University of Vienna were analyzed retrospectively (bilateral antegrade cerebral perfusion: n = 91, 49.5%; unilateral antegrade cerebral perfusion: n = 93, 50.5%). The primary outcome variable was overall survival. Subgroup analyses were performed in patients requiring antegrade cerebral perfusion durations of 50 minutes or more and less than 50 minutes. Secondary outcome variables were 30-day mortality, adverse outcome, permanent and temporary neurologic deficits, renal replacement therapy, prolonged ventilation, intensive care unit stay, and hospital stay. Multivariable Cox proportional hazards analysis demonstrated no significant association of bilateral antegrade cerebral perfusion with overall survival (hazard ratio, 0.63; 95% confidence interval, 0.34-1.14, P = .126). Propensity score modeling using the method of inverse probability of treatment weighting confirmed this result...Continue Reading

Citations

Dec 1, 2020·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Toshihito GomibuchiKenji Okada
Dec 31, 2020·Asian Cardiovascular & Thoracic Annals·Wahaj MunirBenjamin Adams
Apr 7, 2021·Surgical Technology International·Leonard PittsJörg Kempfert
Jun 20, 2021·Seminars in Thoracic and Cardiovascular Surgery·Philipp AngleitnerMarek P Ehrlich
Jul 29, 2021·JTCVS Techniques·Matt P FalasaThomas M Beaver

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