PMID: 20126861Feb 4, 2010Paper

Bilateral testicular tumors caused by congenital adrenal rest hyperplasia

Arquivos brasileiros de endocrinologia e metabologia
Virginia Oliveira FernandesRenan Magalhães Montenegro

Abstract

Testicular tumors are a rare condition associated with congenital adrenal hyperplasia (CAH), originated from intratesticular adrenal rest tumors, and they are rarely associated with malignant tumors. Their histological differentiation from Leydig-cell tumors is quite difficult, which would lead to inappropriate orchiectomies. Thus the objective of this report was to present this diagnostic dilemma. Reported the case of 16-yr-old boy with previous diagnosis of CAH with bilateral testicular enlargement who was recommended to be submitted to a bilateral orchiectomy. Considering this findings, it was decided to treat conventionally with prednisone with significant reduction of testicular volume, and normalization of androgens levels. This case shows the importance of intratesticular adrenal rest tumors in the differential diagnosis of testicular tumors. Cautious approach during investigation and treatment are recommended to avoid inappropriate orchiectomies.

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Citations

Nov 10, 2011·São Paulo Medical Journal = Revista Paulista De Medicina·Giovanni Scala MarchiniMiguel Srougi
May 11, 2019·Journal of Pediatric Endocrinology & Metabolism : JPEM·Gabriela WerneckIvani N Silva
Aug 25, 2017·International Journal of Endocrinology and Metabolism·Laura Ohana Marques Coelho de CarvalhoIzabel Calland Ricarte Beserra

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