PMID: 9165519Apr 1, 1997Paper

Bilateral tonic-clonic epileptic seizures in non-benign familial neonatal convulsions

Pediatric Neurology
I AlfonsoJ Aicardi

Abstract

We report an electroclinical pattern considered characteristic of benign familial neonatal convulsions (BFNC) in two neonates without BFNC. Both neonates were products of uncomplicated pregnancies, labor, and deliveries. The cause of the seizures was not established. There was no family history of seizures or epilepsy. Seizures started on the second and third days after birth. Ten seizures were captured by continuous video-EEG telemetry. The electroclinical events began with generalized tonic posturing coinciding with the appearance of diffuse attenuation of the EEG activity. After several seconds, bilateral clonic movements accompanied by bilateral repetitive sharp waves or spikes occurred in the EEG. One patient had normal development; the other became autistic. We conclude that the electroclinical pattern occurring in BFNC can occur in other types of neonatal seizures.

References

Jul 1, 1990·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·D K Miles, G L Holmes
Dec 1, 1993·Annals of Neurology·E HirschC Marescaux

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Citations

Apr 20, 2010·Pflügers Archiv : European journal of physiology·Snezana MaljevicHolger Lerche
Jun 12, 2002·Pediatric Neurology·Maria P GuerraJanet M Rennie
May 1, 1998·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·E J Novotny
Feb 2, 2008·The Journal of Physiology·Snezana MaljevicHolger Lerche

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