Bilateral transcutaneous tibial nerve stimulation for chronic constipation

Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland
F IqbalC J Vaizey

Abstract

Chronic constipation is difficult to treat when symptoms are intractable. Colonic propulsion may be altered by distal neuromodulation but this is conventionally delivered percutaneously. Transcutaneous tibial nerve stimulation is noninvasive and cheap: this study aimed to assess its efficacy in chronic constipation. Eighteen patients (median age 46 years, 12 female) with chronic constipation were recruited consecutively. Conservative and behavioural therapy had failed to improve symptoms in all 18. Thirty minutes of daily bilateral transcutaneous tibial nerve stimulation was administered by each patient at home for 6 weeks. The primary outcome measure was a change in the Patient Assessment of Constipation Quality of Life (PAC-QoL) score. Change in Patient Assessment of Constipation Symptoms (PAC-SYM), weekly bowel frequency and visual analogue scale (VAS) score were also measured. Fifteen patients (12 female) completed the trial. The PAC-QoL score improved significantly with treatment [pretreatment, median 2.95, interquartile range (IQR) 1.18; posttreatment, median 2.50, IQR 0.70; P = 0.047]. There was no change in PAC-SYM score (pretreatment, median 2.36, IQR 1.59; posttreatment, median 2.08, IQR 0.92; P = 0.53). Weekly stool ...Continue Reading

References

Jan 1, 1989·Diseases of the Colon and Rectum·A Sonnenberg, T R Koch
Jul 1, 1988·Gut·M A KammJ E Lennard-Jones
Dec 22, 1998·Diseases of the Colon and Rectum·P C Shellito
Oct 16, 1999·Scandinavian Journal of Gastroenterology·L FrankP Miner
Feb 7, 2001·Brain : a Journal of Neurology·D I HobdayD G Thompson
Feb 28, 2002·World Journal of Surgery·Andrew J MaloufMichael A Kamm
Jun 26, 2002·The British Journal of Surgery·N J KenefickM A Kamm
Jan 20, 2005·Journal of Clinical Nursing·Hannah Brown, Jacqueline Randle
Apr 30, 2005·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·M ScarpaM R B Keighley
Jul 23, 2005·Scandinavian Journal of Gastroenterology·Patrick MarquisOlivier Chassany
Oct 29, 2005·American Journal of Physiology. Gastrointestinal and Liver Physiology·Masahiro IwaToku Takahashi
Jan 17, 2007·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·P G DinningI J Cook
Jun 27, 2008·The British Journal of Surgery·T C DuddingM A Kamm
Jul 26, 2008·American Journal of Physiology. Gastrointestinal and Liver Physiology·Jie ChenJ D Z Chen
Sep 17, 2008·Gastroenterology Clinics of North America·Satish S C Rao
May 26, 2009·British Journal of Nursing : BJN·Barbara Borwell
Aug 4, 2009·Best Practice & Research. Clinical Gastroenterology·Adeel Bajwa, Anton Emmanuel
Oct 15, 2009·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·I J CookS M Scott
Mar 9, 2010·Gut·Michael A KammCor Baeten
Jun 17, 2010·Diseases of the Colon and Rectum·Yasuko MaedaSøren Laurberg
Nov 12, 2010·International Journal of Colorectal Disease·John M Findlay, Charles Maxwell-Armstrong
Sep 14, 2011·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·B CollinsY Maeda
Apr 4, 2013·The American Journal of Chinese Medicine·Chien-Yue ChenJing-Rhong Chen
Jul 16, 2013·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·J SongJ D Z Chen
Aug 10, 2013·Diseases of the Colon and Rectum·Gregory P ThomasCarolynne J Vaizey
Oct 15, 2013·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·G P ThomasC J Vaizey
Jan 22, 2014·The British Journal of Surgery·E J HorrocksC H Knowles
Dec 6, 2014·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·C RattoUNKNOWN GINS
Jan 6, 2015·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·P G DinningP A Bampton
Jan 22, 2015·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Y MaedaUNKNOWN European SNS Bowel Study Group
Feb 24, 2015·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·M Jiménez-ToscanoJ A Rueda Orgaz
Mar 27, 2015·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·W GrafU Karlbom
Apr 29, 2015·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·G P ThomasC J Vaizey

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Citations

Mar 10, 2017·Expert Review of Gastroenterology & Hepatology·Jiande D Z ChenWei Wei
Dec 19, 2017·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·D StrijbosL P L Gilissen
Sep 2, 2016·Current Opinion in Pediatrics·Peter L Lu, Carlo Di Lorenzo
Nov 7, 2019·Nature Reviews. Gastroenterology & Hepatology·Mana H VriesmanMarc A Benninga
Oct 7, 2017·Alimentary Pharmacology & Therapeutics·Y YiannakouR Kerstens
Jun 2, 2018·Evidence-based Complementary and Alternative Medicine : ECAM·Zhenyang GeJiande D Z Chen
Sep 27, 2018·Cold Spring Harbor Perspectives in Medicine·Larry MillerAnil Vegesna
Feb 6, 2020·Neuromodulation : Journal of the International Neuromodulation Society·Bridget R Southwell
Feb 28, 2020·International Journal of Rehabilitation Research. Internationale Zeitschrift Für Rehabilitationsforschung. Revue Internationale De Recherches De Réadaptation·Jiro NakanoYoko Kusuba
Oct 8, 2020·Arquivos De Gastroenterologia·Hugo Parra de CamargoMarley Ribeiro Feitosa
Feb 9, 2017·Diseases of the Colon and Rectum·Christopher Chan

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