Bilateral treatment for alopecia areata

Pediatric Dermatology
Daniele Torchia, Lawrence A Schachner

Abstract

A 4-year-old, otherwise healthy white girl was referred for a 15-month history of alopecia areata. Anthralin 0.1% cream was prescribed for the left side of the scalp, while corticosteroids for the right side. After 4 months, only the right side of the scalp showed hair regrowth. Half-side strategy, that is, treating one side and managing the other--divided by the mid sagittal suture--as an internal control for no treatment, placebo or other treatment, has been commonly used in clinical studies for decades. In everyday practice, bilateral treatment is useful to evaluate the responsiveness to two topically delivered interventions and diminishes the time necessary to identify an effective one.

References

Nov 12, 1977·Lancet·R Happle, K Echternacht
Nov 18, 2003·The British Journal of Dermatology·S P MacDonald HullUNKNOWN British Association of Dermatologists
Oct 26, 2006·Journal of the European Academy of Dermatology and Venereology : JEADV·Antonella TostiMassimo Milani
Feb 3, 2007·International Journal of Dermatology·Dan WassermanAmy McMichael

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Citations

Sep 12, 2014·International Journal of Dermatology·Virendra N SehgalAnanta Khurana
Jan 4, 2017·Pediatric Dermatology·Mustafa Özdemir, Ali Balevi
May 11, 2019·Journal of Cosmetic Dermatology·Waleed Albalat, Howyda M Ebrahim

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