PMID: 11921129Mar 29, 2002Paper

Bilaterally coherent tremor resembling enhanced physiological tremor: report of three cases

Movement Disorders : Official Journal of the Movement Disorder Society
John D O'SullivanP Brown

Abstract

The contribution of the central nervous system to tremor pathogenesis is unclear. Poor side-to-side coherence in physiological, essential, and parkinsonian tremors suggests distinct bilateral generators. By contrast, significant bilateral coherence demonstrated in orthostatic tremor and in enhanced physiological tremor (EPT) in patients with persistent mirror movements favours single or closely linked bilateral oscillators. We describe three patients (aged 21-37 years) who developed unusual bilateral postural and kinetic tremors at 6-13 Hz resembling EPT. The tremor involved all limbs, and in two cases the face or jaw, in the absence of other significant neurological features. Significant side-to-side coherence was demonstrated in each case using cross-correlation of electromyographic recordings from homologous muscle pairs. We postulate that these unusual tremors originate from a single brainstem source or from bilateral oscillators closely linked at or below this level.

References

Jan 1, 1978·Electroencephalography and Clinical Neurophysiology·R J Elble, J E Randall
Apr 1, 1992·Journal of Neurology·T C BrittonC D Marsden
Feb 1, 1991·Journal of Neurology, Neurosurgery, and Psychiatry·M HallettC D Marsden
Jun 1, 1986·Archives of Neurology·P D ThompsonC D Marsden
Aug 1, 1969·Electroencephalography and Clinical Neurophysiology·C D MarsdenR S Watson
Aug 1, 1984·Archives of Neurology·K M Heilman
Nov 1, 1995·Electroencephalography and Clinical Neurophysiology·M MayerA Danek
Aug 1, 1993·Developmental Medicine and Child Neurology·P Rasmussen
Mar 21, 1998·Neuroscience Letters·B KösterC H Lücking
Aug 13, 1999·Journal of Neurophysiology·D M HallidayJ R Rosenberg
Nov 26, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·M LaukC H Lücking
Jan 14, 2000·Movement Disorders : Official Journal of the Movement Disorder Society·J RaethjenG Deuschl
Jan 29, 2000·Brain : a Journal of Neurology·J H McAuleyC D Marsden
May 3, 2000·Lancet·R J Elble
Aug 6, 2000·Movement Disorders : Official Journal of the Movement Disorder Society·J M HurtadoK A Sigvardt
Feb 15, 2001·Journal of Motor Behavior·Ruiping Xia, Graham Barnes

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Citations

Jun 11, 2010·Proceedings of the National Academy of Sciences of the United States of America·Elizabeth R WilliamsStuart N Baker
Nov 3, 2007·Parkinsonism & Related Disorders·S MorrisonP Silburn
Apr 28, 2007·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·T W BoonstraP J Beek
Jan 1, 2008·Movement Disorders : Official Journal of the Movement Disorder Society·Alexander G MuntsMarina A J Tijssen
Nov 30, 2007·Movement Disorders : Official Journal of the Movement Disorder Society·Graham KerrPeter Silburn
May 17, 2003·Journal of Neurophysiology·Pascal Grosse, Peter Brown
Mar 11, 2017·Experimental Brain Research·Steven MorrisonJustin J Kavanagh

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