PMID: 1211451Sep 1, 1975Paper

Bile acid kinetics and bile secretion in the pony

The American Journal of Physiology
M S AnwerR D Klentz

Abstract

Bile acid pool size and synthesis rate were determined by both isotope-dilution and washout methods in ponies with chronic external biliary fistulas. Bile acid pool size (10.9 mumol/kg) and synthesis rate (11.2 mumol/day per kg) estimated by the isotope-dilution method did not differ significantly from pool size (9.4 mumol/kg) and synthesis rate (9.5 mumol/day per kg) estimated by washout method. Bile acid-dependent and -independent fractions of bile flow, determined by a method that circumvents any inevitable correlation of flow to bile acid secretion due to common factors in both parameters, did not differ from those values obtained by linear regression of bile flow versus bile acid secretion. The choleretic effect of infused chenodeoxycholic acid was higher than that of both endogenous bile acid and infused taurocholic acid.

Citations

Sep 1, 1987·Journal of Veterinary Pharmacology and Therapeutics·M H CourtM Clark
Apr 1, 1985·Veterinary Research Communications·M E Parraga, J J Kaneko
May 12, 1998·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·C B AndreasenE D Lassen
Sep 1, 1982·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M S Anwer, D Hegner
Apr 1, 1995·European Journal of Clinical Investigation·D GleesonR H Dowling
Jan 1, 1992·Veterinary Research Communications·J J KanekoG P Carlson
Jan 18, 2005·Equine Veterinary Journal·D LittleA T Blikslager
Nov 1, 1979·Analytical Biochemistry·M S Anwer, D Hegner

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