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Bile acids. XLVII. 12alpha-Hydroxylation of precursors of allo bile acids by rabbit liver microsomes

Biochimica Et Biophysica Acta

Nov 21, 1975

S S Ali, W H Elliott

PMID: 65

Abstract

Rabbit liver microsomal preparations fortified with 0.1 mM NADPH effectively promote hydroxylation of [3beta-3H]- or [24-14C]allochenodeoxycholic acid or [5alpha,6alpha-3H2]5alpha-cholestane-3alpha,7alpha-diol to their respective 12alpha-hydroxyl derivatives in yields of about 25 or 65%...read more

Mentioned in this Paper

Enzyme Inhibitor Drugs
Sterol 12-alpha-Hydroxylase
Bile Acid Measurement
Allopurinol
Derivatives
9,10-epoxystearic acid, 14C-acid
Senility
Hydroxyl group
Microsomes, Liver
Protein Hydroxylation
24
1
Paper Details
References

Bile acids. XLVII. 12alpha-Hydroxylation of precursors of allo bile acids by rabbit liver microsomes

Biochimica Et Biophysica Acta

Nov 21, 1975

S S Ali, W H Elliott

PMID: 65

DOI:

Abstract

Rabbit liver microsomal preparations fortified with 0.1 mM NADPH effectively promote hydroxylation of [3beta-3H]- or [24-14C]allochenodeoxycholic acid or [5alpha,6alpha-3H2]5alpha-cholestane-3alpha,7alpha-diol to their respective 12alpha-hydroxyl derivatives in yields of about 25 or 65%...read more

Mentioned in this Paper

Enzyme Inhibitor Drugs
Sterol 12-alpha-Hydroxylase
Bile Acid Measurement
Allopurinol
Derivatives
9,10-epoxystearic acid, 14C-acid
Senility
Hydroxyl group
Microsomes, Liver
Protein Hydroxylation
24
1

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