PMID: 1214546Sep 10, 1975Paper

Bile and stress ulcer in the rat (author's transl)

Langenbecks Archiv für Chirurgie
V Schumpelick

Abstract

The influence of bile on the ulcer formation under "restraint stress" condition was studied in rats with direct choledocho-gastrostomia resp. bile duct ligation. After 9 hrs. of immobilisation in plaster cuffs the animals with unrestricted bile flow via the choledochosstress gastrostomia showed as many ulcers as the sham-operated controls. There was no difference in the ulcer localisation, the region of the bile duct anastomosis was without any ulcer. After bile duct ligation the ulcer frequency was reduced to the half. These results are explained by a massive bile reflux under stress condition, of which the pathogenetic role in stress ulcer formation is discussed.

References

Jan 1, 1975·Langenbecks Archiv für Chirurgie·V Schumpelick, B Rauchenberger
Jan 1, 1972·Digestion·H W Davenport
Dec 16, 1972·Lancet·J J Skillman, W Silen
Apr 1, 1962·The American Journal of Physiology·D A BRODIEO M MORENO
Aug 1, 1951·Proceedings of the Society for Experimental Biology and Medicine·F S CROSS, O H WANGENSTEEN

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Citations

Dec 30, 1975·Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie·V Schumpelick, D Grossner
Dec 14, 1977·Langenbecks Archiv für Chirurgie·V SchumpelickG Kessler
Jan 1, 1980·Langenbecks Archiv für Chirurgie·H H LauterbachB Bültmann
Dec 14, 1977·Langenbecks Archiv für Chirurgie·V SchumpelickH W Schreiber
Dec 14, 1977·Langenbecks Archiv für Chirurgie·V SchumpelickM Doehn
Feb 1, 1979·Experimental Aging Research·W P ParéK E Isom

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