Bile compound-induced DNA damage and repair in bacteriophage T4

Toxicology in Vitro : an International Journal Published in Association with BIBRA
A Babatola, C Bernstein

Abstract

Two bile acids (cholic acid and chenodeoxycholic acid) and two bile salts (sodium cholate and sodium deoxycholate) were shown to inactivate bacteriophage T4. The inactivation was largely reversed when the phage was allowed to undergo recombinational repair, indicating that bile compounds cause DNA damage.

References

Feb 1, 1979·American Journal of Epidemiology·L G DalesS R Williams
Oct 15, 1977·Journal of Molecular Biology·E M Nonn, C Bernstein
Oct 1, 1985·Mutation Research·J Watabe, H Bernstein
Jan 1, 1986·Journal of Hepatology·G Paumgartner
Jan 1, 1985·Chemico-biological Interactions·M S Kulkarni, K L Yielding
Feb 1, 1973·British Journal of Cancer·B S Drasar, D Irving
Jul 7, 1983·Nature·B Bridges
Jun 1, 1980·Virology·G E HolmesH Bernstein

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacteriophage: Phage Therapy

Phage therapy uses bacterial viruses (bacteriophages) to treat bacterial infections and is widely being recognized as an alternative to antibiotics. Here is the latest research.