Biliary complications following liver transplantation: single-center experience

Transplantation Proceedings
M PacholczykW Rowiński

Abstract

Biliary complications (BC) following orthotopic liver transplantation (OLT) remain one of the major causes of postoperative complications and treatment failures. The list of common BC consists of biliary stricture, fistula, ischemic type biliary lesions (ITBL), cholangitis, and bile leakage following T-drain removal. Between July 2000 and December 2004, 101 consecutive cadaveric OLTs were performed in our institution. All but three were first full-size grafts. Seventeen patients were transplanted from the urgent list, the remaining 84 (83.16%) from the elective list. All but three patients had a choledochocholedochostomy over a straight drain. Bile cultures were taken routinely. The bile drain was removed following cholangiography 6 weeks after OLT. All patients received antibiotic prophylaxis. Ursodeoxycholic acid was used in selected cases. During the first 6 weeks positive bile cultures in absence of clinical and biochemical symptoms of cholangitis were found in 61 (60.4%) cases. Symptomatic cholangitis requiring antibiotic treatment was observed in 19 (18.8%) patients during the first 6 weeks. Two patients required endoscopic sphincterotomy and temporary stenting due to anastomotic stricture (1) or papilla of Vater fibrosis...Continue Reading

References

Oct 8, 2003·Transplantation Proceedings·W PatkowskiM Krawczyk

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Citations

Aug 15, 2014·American Journal of Surgery·Lisa M McElroyDaniela P Ladner
Dec 11, 2007·Der Pathologe·U Drebber, H P Dienes
Feb 1, 2011·Der Pathologe·U DrebberH P Dienes

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