Get paper from

journal cover

Biliary excretion of colchicine in newborn rats

Drug Metabolism and Disposition : the Biological Fate of Chemicals

Jan 1, 1975

Arwen L Hunter, Curtis D Klaassen

PMID: 1230

Get paper from

Abstract

The 24-hr LD50 of colchicine in newborn rats is 0.24 mg/kg, which is about 1/10 that observed in the adult. The 24-hr LD50 of colchicine was relatively constant in rats over 25 days of age. In an attempt to determine the mechanism of the increased sensitivity of the newborn rat to the t...read more

Mentioned in this Paper

Lethal Dose 50
Liver
Biliary Sludge
Colchicine, (R)-Isomer
Paper Details
References
    • References
    • Citations

      References currently unavailable

      We're still populating references for this paper, please check back later.
    • References
    • Citations

      No citations available

      This paper may not have been cited yet.
  • Biliary excretion of colchicine in newborn rats

    Drug Metabolism and Disposition : the Biological Fate of Chemicals

    Jan 1, 1975

    Arwen L Hunter, Curtis D Klaassen

    PMID: 1230

    DOI:

    Abstract

    The 24-hr LD50 of colchicine in newborn rats is 0.24 mg/kg, which is about 1/10 that observed in the adult. The 24-hr LD50 of colchicine was relatively constant in rats over 25 days of age. In an attempt to determine the mechanism of the increased sensitivity of the newborn rat to the t...read more

    Mentioned in this Paper

    Lethal Dose 50
    Liver
    Biliary Sludge
    Colchicine, (R)-Isomer

    Related Papers

    Paper Details
    References
    • References
    • Citations

      References currently unavailable

      We're still populating references for this paper, please check back later.
    • References
    • Citations

      No citations available

      This paper may not have been cited yet.
  • Get paper from

    © 2019 Meta ULC. All rights reserved.
    /papers/biliary-excretion-of-colchicine-in-newborn/1230