Biliary lipid composition in early childhood.

Clinica Chimica Acta; International Journal of Clinical Chemistry
J Von BergmannG Paumgartner

Abstract

The biliary lipid composition was studied in 11 children without hepatic or gastrointestinal disease who ranged in age from 15 to 54 months. The molar percentages of cholesterol, bile acids and phospholipids in the biliary lipid mixture averaged 5.0 +/- 1.1; 80 +/- 6.1 and 15 +/- 6.2%, respectively. Cholic, chenodeoxycholic, deoxycholic and ursodeoxycholic acid comprised 48; 45; 4 and 3% of total bile acids, respectively. A comparison of the lipid composition with data reported in the literature for the adult reveals that the molar percentage of cholesterol is relatively low in early childhood. This could be one of the factors which is responsible for the low incidence of cholesterol gallstones in this age group.

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Citations

Dec 15, 1977·The New England Journal of Medicine·C C RoyR Lasalle
Oct 1, 1983·Archives of Disease in Childhood·Y TazawaK Tada
Dec 1, 1986·European Journal of Clinical Investigation·K Von BergmannO Leiss
Aug 1, 1996·Journal of Pediatric Gastroenterology and Nutrition·Z HalpernY Bujanover

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