PMID: 9193774Oct 1, 1996Paper

Biliary sludge: a risk factor for 'idiopathic' pancreatitis?

Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie
P J MarottaD H Taves

Abstract

Idiopathic acute pancreatitis is common. Recent evidence suggests that biliary sludge may be the etiology in many patients with this disorder. In this case-control study, admission ultrasound examinations of patients with idiopathic pancreatitis, patients with acute alcohol-associated pancreatitis and a control group were compared. Biliary sludge was found in seven of 21 patients (33%) with idiopathic pancreatitis, two of 25 (8%) with acute alcohol-associated pancreatitis and one of 63 controls (1.6%). Comparison of idiopathic pancreatitis patients with both acute alcohol-associated pancreatitis patients and controls for the presence of sludge revealed odds ratios of 31.0 (95% CI 3.5 to 273) and 5.8 (95% CI 1.1 to 32.0), respectively. Also observed was a trend towards higher levels of liver enzymes, bilirubin and amylase in patients with idiopathic pancreatitis who had sludge identified. This study provides further evidence linking biliary sludge with a significant proportion of patients with idiopathic acute pancreatitis.

Citations

Oct 15, 2008·Pancreas·Charles Mel Wilcox, Meredith Kilgore
Jan 14, 2010·Revista do Colégio Brasileiro de Cirurgiões·José Celso ArdenghJosé Flávio Coelho
Dec 11, 2014·World Journal of Gastroenterology : WJG·Pier Alberto Testoni

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