PMID: 15377477Sep 21, 2004Paper

Bilineage acute leukemia of T-lymphoid and myeloid lineages

Haematologica
Norimoto KobayashiKenichi Koike

Abstract

We report the case of a child with Philadelphia chromosome-negative bilineage leukemia characterized by the coexistence of T-cell leukemia and myelomonocytic leukemia. Comparative analyses of genetic markers and proliferative/differentiative potential show the possibility of malignant transformation of a T-lineage stem cell with the potential to differentiate into the myeloid lineage.

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