PMID: 29755343DOI: 10.3389/fphar.2018.00303May 15, 2018Paper
Bilirubin Oxidation Products and Cerebral Vasoconstriction
Frontiers in Pharmacology
Robert M Rapoport
Abstract
Key evidence in support of the hypothesis that bilirubin oxidation products (BOXes) contribute to the vasoconstriction associated with subarachnoid hemorrhage (SAH) are the (1) presence of BOXes in cerebral spinal fluid from SAH patients and (2) ability of one or more BOXes to elicit vasoconstriction. We critically evaluate this key evidence, detail where gaps remain, and describe recent approaches that will address these gaps.
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Citations
Apr 24, 2019·Neurocritical Care·Joseph R GeraghtyFernando D Testai
Preliminary results in the analysis of the immune response after aneurysmal subarachnoid hemorrhage.
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Dec 7, 2021·Accounts of Chemical Research·Elisa Tomat, Clayton J Curtis
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