PMID: 8956486Oct 30, 1996Paper

Binding and relaxation behaviour of prodan and patman in phospholipid vesicles: a fluorescence and 1H NMR study

Biophysical Chemistry
R HuttererMartin Hof

Abstract

The relative location, binding behaviour and the solvent relaxation behaviour of the polarity sensitive membrane probes 6-propionyl-2-(dimethylamino)naphthalene and 6-palmitoyl-2-[[trimethylammoniumethyl]methylamino]naphthalene chloride in vesicles composed of 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine or egg yolk lecithin have been compared using steady-state and time-resolved fluorescence as well as high resolution NMR measurements. The reconstructed time-resolved emission spectra show unambiguously that the observed spectral shifts in vesicle systems have to be assigned to time-dependent solvent relaxation processes rather than to a probe relocation mechanism. All fluorescence as well as the NMR relaxation data suggest a deeper localization of Patman in the membrane, sensing a less polar and/or more restricted probe environment.

References

Oct 1, 1988·British Journal of Rheumatology·P G WhiteA K Clarke
Mar 6, 1974·Journal of the American Chemical Society·G W Feigenson, S I Chan
Jan 1, 1982·Haemostasis·R F Zwaal, H C Hemker

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Citations

Dec 6, 2005·Journal of Fluorescence·Piotr JurkiewiczMartin Hof
Jan 6, 2012·Journal of Fluorescence·Valeriya M TrusovaGalyna P Gorbenko
Feb 25, 2003·Chemistry and Physics of Lipids·Amitabha Chattopadhyay
Aug 29, 1998·Chemistry and Physics of Lipids·A de la MazaJ L Parra
Dec 21, 2006·Biochimica Et Biophysica Acta·Gaëlle Le GoffRonald J Clarke
Sep 8, 2012·Biochimica Et Biophysica Acta·Hannabeth FranchinoJohn D Bell
Feb 15, 2012·The Journal of Physical Chemistry. B·William K NitschkeHubert Stassen
Apr 19, 2007·Chemistry, an Asian Journal·Pratik SenKeisuke Tominaga
Jan 15, 2013·Langmuir : the ACS Journal of Surfaces and Colloids·Justyna Barucha-KraszewskaChristophe Ramseyer
Oct 4, 2006·Langmuir : the ACS Journal of Surfaces and Colloids·Piotr JurkiewiczMartin Hof
Jul 21, 2006·The Journal of Physical Chemistry. B·Pratik SenKankan Bhattacharyya
Jun 28, 2006·The Journal of Physical Chemistry. B·Fernando MoyanoN Mariano Correa
Jan 23, 1999·Biophysical Journal·O P Bondar, E S Rowe
Mar 17, 2006·The Journal of Physical Chemistry. B·Anjan ChakrabortyNilmoni Sarkar

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