PMID: 3768715Oct 15, 1986Paper

Binding of 125I-cholecystokinin-octapeptide in the paraventricular but not the supraoptic nucleus is increased by ovariectomy

Brain Research
T R Akesson, P Micevych

Abstract

Specific, high affinity binding of 125I-cholecystokinin-octapeptide (CCK) in the paraventricular nucleus was found to be confined to the anterior pole of the posterior magnocellular subdivision (PVHpm). Tissue sampled from intact male and female rats revealed only low CCK binding in the PVHpm; however, binding was greatly increased by ovariectomy. By contrast, binding was uniformly high throughout the supraoptic nucleus of intact males and females and was unaffected by ovariectomy. These results are interpreted in terms of the potential influence of CCK and estrogen on neurosecretion of oxytocin and CCK.

References

Jan 1, 1985·Annals of the New York Academy of Sciences·P GaudreauR Quirion
Jul 11, 1985·European Journal of Pharmacology·C R Mantyh, P W Mantyh
Jan 1, 1984·Neurochemistry International·S GoldmanJ J Vanderhaeghen

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Citations

Jun 1, 1993·Physiology & Behavior·P C ButeraN J Cataldo
Jan 1, 1989·Brain Research. Brain Research Reviews·S M Gardiner, T Bennett
Mar 1, 1995·Progress in Neurobiology·M D Madeira, A R Lieberman
Oct 1, 1990·The Journal of Comparative Neurology·P Ciofi, G Tramu

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