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Binding of bile acids to cholestyramine at gastric pH conditions

Journal of Pharmaceutical Sciences

Nov 1, 1975

S Lindenbaum, Taro Higuchi

PMID: 486

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Abstract

The binding of bile salts to cholestyramine was studied under varying conditions of pH and added electrolyte. The taurine-conjugated bile salts were strongly absorbed by the anion-exchange resin at low pH and in the presence of chloride anions. Glycocholic acid binding was very weak at ...read more

Mentioned in this Paper

Gastric pH
Alkalemia
Electrolyte [EPC]
Electrolytes
Glycine Cholate
Philadelphia Chromosome
Taurocholic Acid, Monolithium Salt
Cholestyramine Resin
Bile Salts
Hydrogen-Ion Concentration
9
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  • Binding of bile acids to cholestyramine at gastric pH conditions

    Journal of Pharmaceutical Sciences

    Nov 1, 1975

    S Lindenbaum, Taro Higuchi

    PMID: 486

    DOI:

    Abstract

    The binding of bile salts to cholestyramine was studied under varying conditions of pH and added electrolyte. The taurine-conjugated bile salts were strongly absorbed by the anion-exchange resin at low pH and in the presence of chloride anions. Glycocholic acid binding was very weak at ...read more

    Mentioned in this Paper

    Gastric pH
    Alkalemia
    Electrolyte [EPC]
    Electrolytes
    Glycine Cholate
    9

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