PMID: 3770168Sep 1, 1986Paper

Binding of cardiac glycosides by the erythrocytes of patients

Farmakologiia i toksikologiia
V V Bakaev

Abstract

Digoxin and strophanthin K uptake by patients' red cells was investigated by the Rb-86 assay. It was found that digoxin and strophanthin K levels in red cells increased with augmentation of the drugs concentrations in plasma, the ratio of cardiac glycoside levels in red cells to their concentrations in plasma decreased. The degree of binding to red cells is more pronounced for strophanthin K than for digoxin.

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