Binding of monovalent alkali metal ions with negatively charged phospholipid membranes

Biochimica Et Biophysica Acta
Pabitra MaitySanat Karmakar

Abstract

We have systematically investigated the effect of various alkali metal ions with negatively charged phospholipid membranes. Size distributions of large unilamellar vesicles have been confirmed using dynamic light scattering. Zeta potential and effective charges per vesicle in the presence of various alkali metal ions have been estimated from the measured electrophoretic mobility. We have determined the intrinsic binding constant from the zeta potential using electrostatic double layer theory. The reasonable and consistent value of the intrinsic binding constant of Na(+), found at moderate NaCl concentration (10-100 mM), indicates that the Gouy-Chapman theory cannot be applied for very high (> 100mM) and very low (< 10 mM) electrolyte concentrations. The isothermal titration calorimetry study has revealed that the net binding heat of interaction of the negatively charged vesicles with monovalent alkali metal ions is small and comparable to those obtained from neutral phosphatidylcholine vesicles. The overall endothermic response of binding heat suggests that interaction is primarily entropy driven. The entropy gain might arise due to the release of water molecules from the hydration layer vicinity of the membranes. Therefore, th...Continue Reading

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Citations

Nov 2, 2016·Langmuir : the ACS Journal of Surfaces and Colloids·Shih-Ting LinShih-Huang Tung
Feb 10, 2017·The Journal of Physical Chemistry. B·Achinta SannigrahiKrishnananda Chattopadhyay
Nov 12, 2017·The Journal of Membrane Biology·Eric JakobssonLaura Pritchet
Jan 14, 2018·The Journal of Membrane Biology·Ran Friedman
Jan 30, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·Rui CaoAnthony D Dinsmore
Mar 13, 2020·Langmuir : the ACS Journal of Surfaces and Colloids·Animesh HalderSanat Karmakar
Mar 25, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·Dennis J MichalakDavid P Hoogerheide
May 14, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·Sarah E Zuraw-WestonAnthony D Dinsmore
Dec 14, 2017·Langmuir : the ACS Journal of Surfaces and Colloids·Toshinori MotegiRyugo Tero
Oct 15, 2019·Langmuir : the ACS Journal of Surfaces and Colloids·D GilbileT L Kuhl
Aug 29, 2019·ACS Omega·Candelaria I CámaraNatalia Wilke
Nov 28, 2017·Langmuir : the ACS Journal of Surfaces and Colloids·Yibo Liu, Juewen Liu
Jul 31, 2018·Langmuir : the ACS Journal of Surfaces and Colloids·Pabitra MaitySanat Karmakar
Jul 21, 2020·The Journal of Physical Chemistry Letters·Evelyne DeplazesAlvaro Garcia
Nov 5, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·Anand Kumar Sahu, Ashok Kumar Mishra

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