PMID: 9658142Jul 11, 1998Paper

Binding of murine leukemia virus Gag polyproteins to KIF4, a microtubule-based motor protein

Journal of Virology
W KimH C Morse

Abstract

A cDNA clone encoding a cellular protein that interacts with murine leukemia virus (MuLV) Gag proteins was isolated from a T-cell lymphoma library. The sequence of the clone is identical to the C terminus of a cellular protein, KIF4, a microtubule-associated motor protein that belongs to the kinesin superfamily. KIF4-MuLV Gag associations have been detected in vitro and in vivo in mammalian cells. We suggest that KIF4 could be involved in Gag polyprotein translocation from the cytoplasm to the cell membrane.

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Dec 1, 2004·Annual Review of Genetics·Stephen P Goff
Apr 22, 2006·The EMBO Journal·Juliana LeungStephen P Goff
Jul 27, 2002·Annual Review of Cell and Developmental Biology·Gregory A Smith, Lynn W Enquist
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Mar 21, 2006·Retrovirology·Alan W CochraneAndrew J Mouland

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