Binocular cross-orientation suppression in the cat's striate cortex

Journal of Neurophysiology
G A WalkerR D Freeman

Abstract

When a cortical cell is activated by an optimal sinusoidal grating, its response can be attenuated by a superimposed second grating oriented orthogonally to the optimal stimulus. This effect is known as cross-orientation suppression (COS). In previous work, monocular characteristics have been explored and interocular tests have been conducted in an attempt to locate the origin of the suppression. In this study, we have recorded extracellularly from cortical cells to investigate the binocular characteristics of COS. Our hypothesis is that binocular disparity influences the strength of the effect. Our results do not support this supposition. We find that binocular COS is as strong as monocular COS, but disparity changes are of no consequence. We also conducted interocular tests in which the optimal grating and the orthogonal mask were seen by separate eyes. Although most interocular effects were weak, they were present in almost every cell and spanned a wide range of suppression strengths. We also tested the effect of asynchronous presentation of optimal and orthogonal gratings. These temporal offsets did not affect the strength of COS. We conclude that the suppressive mechanism underlying COS is primarily monocular and acts prio...Continue Reading

References

Aug 1, 1992·Visual Neuroscience·D J Heeger
Jul 1, 1992·Journal of Neurophysiology·G C DeAngelisR D Freeman
Jan 1, 1991·Vision Research·D G Pelli, L Zhang
Jan 1, 1991·Vision Research·B C SkottunA B Bonds
Sep 1, 1988·Quarterly Journal of Experimental Physiology : an International Journal of the Physiological Society·K A Martin
Jan 1, 1987·Experimental Brain Research·F J Varela, W Singer
Jan 1, 1987·Experimental Brain Research·M C MorroneH D Speed
Jan 1, 1987·Experimental Brain Research·J T XueR D Freeman
Jul 1, 1986·Journal of Neurophysiology·I Ohzawa, R D Freeman
Jul 1, 1986·Journal of Neurophysiology·I Ohzawa, R D Freeman
Sep 1, 1985·Journal of Neurophysiology·I OhzawaR D Freeman
Sep 1, 1985·Journal of Neurophysiology·G SclarR D Freeman
Oct 12, 1971·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·L J Garey, T P Powell
Jul 1, 1972·Medical & Biological Engineering·W R Levick
Jan 31, 1970·Nature·C Blakemore, J D Pettigrew
Nov 1, 1967·The Journal of Physiology·H B BarlowJ D Pettigrew
Oct 22, 1982·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·M C MorroneL Maffei
Jan 1, 1994·Journal of Neurophysiology·G C DeAngelisI Ohzawa
Apr 28, 1994·Nature·F Sengpiel, C Blakemore
Jan 1, 1993·Spatial Vision·M von GrünauM Kwas
Nov 1, 1996·Visual Neuroscience·E S GreenR D Freeman

❮ Previous
Next ❯

Citations

Apr 24, 2013·Proceedings of the National Academy of Sciences of the United States of America·Jan BrascampRandolph Blake
Jul 21, 2006·Journal of Neurophysiology·Baowang LiRalph D Freeman
Sep 4, 2008·Visual Neuroscience·Tim S MeeseRobert J Summers
Dec 19, 2008·Journal of Neurophysiology·Rui Kimura, Izumi Ohzawa
Oct 18, 2019·Journal of Vision·Michele A CoxAlexander Maier
May 24, 2017·Annual Review of Vision Science·Nicholas J Priebe
Aug 10, 1999·Neuroreport·J W Morley, R M Vickery
Apr 22, 2005·Journal of Neurophysiology·Baowang LiRalph D Freeman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved