Binocular iPad treatment for amblyopia in preschool children

Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
Eileen E BirchD Stager

Abstract

Recent experimental evidence supports a role for binocular visual experience in the treatment of amblyopia. The purpose of this study was to determine whether repeated binocular visual experience with dichoptic iPad games could effectively treat amblyopia in preschool children. A total of 50 consecutive amblyopic preschool children 3-6.9 years of age were assigned to play sham iPad games (first 5 children) or binocular iPad games (n = 45) for at least 4 hours per week for 4 weeks. Thirty (67%) children in the binocular iPad group and 4 (80%) in the sham iPad group were also treated with patching at a different time of day. Visual acuity and stereoacuity were assessed at baseline, at 4 weeks, and at 3 months after the cessation of game play. The sham iPad group had no significant improvement in visual acuity (t4 = 0.34, P = 0.75). In the binocular iPad group, mean visual acuity (plus or minus standard error) improved from 0.43 ± 0.03 at baseline to 0.34 ± 0.03 logMAR at 4 weeks (n = 45; paired t44 = 4.93; P < 0.0001). Stereoacuity did not significantly improve (t44 = 1.35, P = 0.18). Children who played the binocular iPad games for ≥8 hours (≥50% compliance) had significantly more visual acuity improvement than children who play...Continue Reading

References

Sep 27, 2001·Archives of Ophthalmology·J M HolmesUNKNOWN Pediatric Eye Disease Investigator Group
May 14, 2003·Archives of Ophthalmology·Michael X RepkaUNKNOWN Pediatric Eye Disease Investigator Group
Aug 25, 2004·Investigative Ophthalmology & Visual Science·Catherine E StewartAlistair R Fielder
Nov 4, 2004·Ophthalmology·Michael X RepkaUNKNOWN Pediatric Eye Disease Investigator Group
Jan 27, 2005·Investigative Ophthalmology & Visual Science·Eileen E BirchDianna Hughbanks Wheaton
Feb 16, 2005·Archives of Ophthalmology·Michael X RepkaUNKNOWN Pediatric Eye Disease Investigator Group
Mar 26, 2005·Investigative Ophthalmology & Visual Science·Musarat AwanIrene Gottlob
Jul 8, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Frank Sengpiel, Vasily Vorobyov
Oct 31, 2006·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Eileen E Birch, David R Stager
May 26, 2007·Investigative Ophthalmology & Visual Science·Catherine E StewartUNKNOWN MOTAS Cooperative
Oct 27, 2007·Investigative Ophthalmology & Visual Science·Daniel H BakerRobert F Hess
Sep 24, 2008·Vision Research·B MansouriR F Hess
Feb 19, 2010·Ophthalmology·UNKNOWN Pediatric Eye Disease Investigator Group Writing CommitteeDonny W Suh
Feb 22, 2011·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Long ToJeremy R Cooperstock
Mar 15, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Angela M TjiamHuibert J Simonsz
Dec 16, 2011·Investigative Ophthalmology & Visual Science·Pamela J KnoxMarie Cleary
Dec 4, 2012·Progress in Retinal and Eye Research·Eileen E Birch
Jul 25, 2013·Investigative Ophthalmology & Visual Science·Michael P WallaceUNKNOWN Randomized Occlusion Treatment Amblyopia Study (ROTAS) Cooperatives
Jul 26, 2014·Eye·S L LiE E Birch

❮ Previous
Next ❯

Citations

Mar 3, 2015·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·David G Hunter
Oct 22, 2015·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Simone L LiEileen E Birch
Oct 31, 2006·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Eileen E Birch, David R Stager
Dec 9, 2016·Strabismus·Subhash Dadeya, Sonal Dangda
Feb 20, 2017·Vision Research·Lisa HammBenjamin Thompson
Dec 2, 2017·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Lisa M HammBenjamin Thompson
Feb 3, 2018·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Lisa AsperSieu Khuu
May 20, 2018·The British Journal of Ophthalmology·Courtney L Kraus, Susan M Culican
Jan 11, 2019·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Ann L WebberEileen E Birch
Jun 5, 2019·Journal of Binocular Vision and Ocular Motility·Eileen E BirchDeborah E Giaschi
Sep 9, 2017·International Ophthalmology Clinics·Eric D Gaier, David G Hunter
Oct 1, 2020·Acta Ophthalmologica·Peter C K PangBenjamin Thompson
Feb 1, 2017·Current Opinion in Ophthalmology·Alexander J E Foss
Jun 16, 2018·Visual Neuroscience·Michael P Stryker, Siegrid Löwel
Dec 14, 2019·Korean Journal of Ophthalmology : KJO·Shin Hae Park
Jul 18, 2020·Journal of Ophthalmology·María B Coco-MartinJuan F Arenillas
Aug 1, 2020·Journal of Ophthalmology·Carlos J Hernández-Rodríguez, David P Piñero
May 7, 2016·Current Opinion in Ophthalmology·Aldo Vagge, Leonard B Nelson
May 26, 2018·Investigative Ophthalmology & Visual Science·Angela M ChenT Rowan Candy
Feb 6, 2020·Frontiers in Neuroscience·Yiya ChenRobert F Hess
Aug 23, 2019·Indian Journal of Ophthalmology·Santhan K S GopalAbhishek Pandit
Nov 28, 2020·Translational Vision Science & Technology·Shivalika Sehgal, PremNandhini Satgunam
Dec 16, 2020·Journal of Clinical Medicine·Carlos J Hernández-RodríguezMaría Begoña Coco-Martín
Mar 11, 2021·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Tina Y GaoBenjamin Thompson
Oct 8, 2018·Vision Research·Manuela BossiSteven C Dakin
May 5, 2021·Investigative Ophthalmology & Visual Science·Xiang-Yun LiuJun-Yun Zhang
Jun 1, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Aveen KadhumSjoukje E Loudon
May 28, 2021·Journal of Pediatric Ophthalmology and Strabismus·Zhale RajaviMohammad Reza
Aug 24, 2021·Journal of Medical Internet Research·Chee Wui OngVictor Teck Chang Koh
Nov 28, 2020·Journal of Optometry·Antonio RodánLaura C Jara García

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.