Binodal, wireless epidermal electronic systems with in-sensor analytics for neonatal intensive care

Science
Ha Uk ChungJohn A Rogers

Abstract

Existing vital sign monitoring systems in the neonatal intensive care unit (NICU) require multiple wires connected to rigid sensors with strongly adherent interfaces to the skin. We introduce a pair of ultrathin, soft, skin-like electronic devices whose coordinated, wireless operation reproduces the functionality of these traditional technologies but bypasses their intrinsic limitations. The enabling advances in engineering science include designs that support wireless, battery-free operation; real-time, in-sensor data analytics; time-synchronized, continuous data streaming; soft mechanics and gentle adhesive interfaces to the skin; and compatibility with visual inspection and with medical imaging techniques used in the NICU. Preliminary studies on neonates admitted to operating NICUs demonstrate performance comparable to the most advanced clinical-standard monitoring systems.

References

Jan 1, 1990·Early Human Development·P H CartlidgeN Rutter
Apr 1, 1989·Computer Methods and Programs in Biomedicine·A A KamalA J Mearns
Oct 1, 1988·British Medical Bulletin·N Rutter
Jan 1, 1986·Biology of the Neonate·N J Evans, N Rutter
Mar 1, 1985·IEEE Transactions on Bio-medical Engineering·J Pan, W J Tompkins
Jan 1, 1981·Psychophysiology·L A GeddesW A Tacker
Nov 30, 2000·Medical & Biological Engineering & Computing·W ChenT Togawa
Jun 26, 2002·Journal of Perinatology : Official Journal of the California Perinatal Association·Mariana C BasergaAugusto Sola
Apr 27, 2005·Journal of Wound, Ostomy, and Continence Nursing : Official Publication of the Wound, Ostomy and Continence Nurses Society·Kathleen M McLaneLarry S Jefferson
Oct 20, 2005·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Christer AhlstromPer Ask
Jan 10, 2006·Physiological Measurement·Jung Soo KimKwang Suk Park
Mar 7, 2006·Seminars in Fetal & Neonatal Medicine·Jonathan M Fanaroff, Avroy A Fanaroff
Nov 21, 2008·American Journal of Perinatology·Joyce O'Shea, Eugene M Dempsey
Sep 19, 2009·Journal of Paediatrics and Child Health·Lynn SinclairJohn Sinn
Dec 2, 2009·Pediatrics·Kathrin Puch-KapstRoland R Wauer
Aug 13, 2011·Science·Dae-Hyeong KimJohn A Rogers
Sep 14, 2012·Journal of Paediatrics and Child Health·Christopher D SmyserTerrie E Inder
Jul 3, 2013·Journal of Pediatric Nursing·John S MurrayMartha A Q Curley
Aug 13, 2014·Circulation·Joseph A WalshSteven R Steinhubl
Dec 17, 2014·Scientific Reports·Marty Visscher, Teresa Taylor
Jun 10, 2015·Sensors·Vedat CoskunKerem Ok
Jul 28, 2015·JAMA Pediatrics·Wade Harrison, David Goodman
Oct 26, 2016·Journal of Perinatology : Official Journal of the California Perinatal Association·L MelbourneA N Massaro
Jan 14, 2017·Sensors·Sumit MajumderM Jamal Deen
Feb 6, 2017·Sleep Medicine Reviews·Laurelle A SmithBarbara C Galland
Jun 22, 2017·Nature Communications·Kyung-In JangJohn A Rogers
Aug 11, 2017·Archives of Disease in Childhood. Fetal and Neonatal Edition·Anna C TottmanUNKNOWN PIANO study team
Feb 23, 2018·Biosensors & Bioelectronics·Wenting DangRavinder Dahiya

❮ Previous
Next ❯

Citations

Jun 28, 2019·Advanced Materials·Yinji MaXue Feng
Jun 28, 2019·Nanotechnology·Yiming LiuXinge Yu
Sep 7, 2019·Advanced Materials·Zhaoqian XieJohn A Rogers
Oct 12, 2019·Sensors·Young-Geun ParkJang-Ung Park
Oct 18, 2019·Advanced Materials·Yujia Zhang, Tiger H Tao
Sep 19, 2019·Nanoscale·Yancong QiaoTian-Ling Ren
Nov 14, 2019·Advanced Materials·Yunzhi LingWenlong Cheng
Dec 22, 2019·Sensors·Inyeol YunYoonyoung Chung
Jan 7, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Jianwu WangXiaodong Chen
Nov 20, 2019·Advanced Materials·Yasser KhanAna C Arias
Jul 15, 2020·Proceedings of the National Academy of Sciences of the United States of America·Yadong XuZheng Yan
Jul 19, 2019·Nature·Shuai XuJohn A Rogers
Aug 2, 2019·Science Translational Medicine·Giuseppe Schiavone, Stéphanie P Lacour
Jan 17, 2020·Advanced Materials·Ting WangXiaodong Chen
Mar 13, 2020·Nature Medicine·Prakesh S Shah
Dec 25, 2019·Proceedings of the National Academy of Sciences of the United States of America·Yadong XuZheng Yan
Mar 29, 2020·Science Advances·Yichao ZhaoSam Emaminejad
Jul 11, 2020·Scientific Reports·Heather P DuncanDavid Lowe
Mar 2, 2019·Science·Ruth Guinsburg
May 20, 2019·Current Treatment Options in Cardiovascular Medicine·Shannon WongvibulsinEvan D Muse
Dec 14, 2019·Advanced Science·Hyeon Seok AnJang-Ung Park
Jun 9, 2020·Frontiers in Bioengineering and Biotechnology·Arthur Henri DewolfYury Ivanenko
Jan 25, 2020·Nature Communications·Rongzhou LinJohn S Ho
Oct 10, 2020·Nano Convergence·Abhishek Singh DahiyaRavinder Dahiya
Oct 9, 2020·Research : a Science Partner Journal·Yue LiTing Zhang
Dec 15, 2020·Biomaterials·Yihang ChenGuosong Hong
Jan 28, 2021·Sensors·Sung-Gu KangJeonghyun Kim
Dec 22, 2020·Computers in Biology and Medicine·Yao GuoWei Chen
Feb 17, 2021·Nature Biomedical Engineering·Juliane R SempionattoJoseph Wang

❮ Previous
Next ❯

Methods Mentioned

BETA
imaging techniques
chip

Clinical Trials Mentioned

NCT02865070

Software Mentioned

Surface Pro
ECGEESmodule

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved