Bio-synthesis of peppermint leaf extract polyphenols capped nano-platinum and their in-vitro cytotoxicity towards colon cancer cell lines (HCT 116)

Materials Science & Engineering. C, Materials for Biological Applications
Chuang YangQiang Chi

Abstract

Bio-synthesis of Platinum nanoparticles (Pt NPs) was achieved using Mentha piperita (Peppermint) aqueous leaf extract. Further the ecofriendly synthesized Pt NPs were subjected for various characterization techniques. The characterization results inferred that the green synthesized Pt NPs were said to be in average particle size of 54.3nm. The particles are in spherical shape and it has been entrapped with secondary metabolites (Polyphenols). The polyphenols capped Pt NPs were screened for cytotoxicity against human colon cancer cell line (HCT 116). The results inferred that the ecofriendly synthesized Pt NPs decrease the viability of cancer cells at lower concentrations with IC50 value of 20μg/mL.

Citations

Jul 12, 2017·Chemical Society Reviews·Deborah PedonePier Paolo Pompa
May 8, 2020·Oxidative Medicine and Cellular Longevity·Paola AielloWesam Kooti
Mar 3, 2020·Frontiers in Pharmacology·Felicia PattiRaffaele Pezzani
Nov 22, 2019·Anti-cancer Agents in Medicinal Chemistry·Rumana AhmadArvind K Srivastava
Nov 1, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Sherif Ashraf FahmyHassan Mohamed El-Said Azzazy
Nov 14, 2020·Journal of Nanoscience and Nanotechnology·Yiqun LiuLong Zhao

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