Bioaccumulation of 4-nonylphenol and effects on biomarkers, acetylcholinesterase, glutathione-S-transferase and glutathione peroxidase, in Mytilus galloprovincialis mussel gilla

Environmental Pollution
Leticia Vidal-LiñánRicardo Beiras

Abstract

Wild marine mussels, Mytilus galloprovincialis showed a moderate bioaccumulation ability when exposed to waterborne 4-nonylphenol (4-NP), with a bioconcentration factor (BCF) of 6850 L Kg(-1) (dry weight). Kinetic and concentration-response experiments were performed and three enzymatic biomarkers in mussel gills were measured: Glutathione S-transferase (GST), glutathione peroxidase (GPx) and acetylcholinesterase (AChE). Exposure of mussels to environmentally relevant concentrations (25-100 μg L(-1)) of 4-nonylphenol significantly inhibited the AChE activity and induced the GST and GPx activities. GST induction was dose dependent whilst GPx activity showed a less consistent pattern, but in both cases the induction remained after a 10 d depuration period. Mussels seem capable of eliminating 4-NP from their tissues through a mechanism involving GST induction.

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Citations

Sep 12, 2015·The Science of the Total Environment·L A MaranhoM L Martín-Díaz
Jan 23, 2019·Environmental Science and Pollution Research International·Laura ButrimavičienėJanina Baršienė
Jan 25, 2020·The Science of the Total Environment·Charlene TrestrailDayanthi Nugegoda
Aug 15, 2017·Marine Environmental Research·Jonny BeyerMerete Schøyen

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