Bioaccumulation, oxidative stress and genotoxicity in fish (Channa punctatus) exposed to a thermal power plant effluent

Ecotoxicology and Environmental Safety
Mehjbeen JavedMasood Ahmad

Abstract

Metal bioaccumulation and induction of biomarkers such as lipid peroxidation (LPO), superoxide dismutase (SOD), catalase (CAT), glutathione S transferase (GST), reduced glutathione (GSH) and DNA damage are potential indicators of stress in Channa punctatus exposed to effluents. In canal water, receiving thermal power plant discharges, Fe and Ni concentrations exceeded the recommended guidelines set by the United Nations Environment Programme Global Environment Monitoring System (UNEPGEMS). Fe was highly bioavailable and accumulated in all organs (liver, kidney, muscle and integument). The highest metal pollution index (MPI) value of 41.2 was observed in kidney and the lowest 13.5 in muscle tissue. LPO, SOD, CAT and GST levels were significantly higher in liver and kidney, whereas GSH levels declined significantly compared to fish from the reference site. Concomitant damage to DNA was observed with significantly higher mean tail length in the exposed fish gill cells (26.5µm) and in liver (20.8µm) compared to reference fish. Therefore, it can be concluded that the thermal power plant effluent had the potential to cause oxidative stress and DNA damage in C. punctatus.

References

Jan 1, 1978·Methods in Enzymology·J A Buege, S D Aust
Apr 16, 1975·Journal of the American Chemical Society·M DizdarogluD Schulte-Frohlinde
Mar 1, 1988·Experimental Cell Research·N P SinghE L Schneider
Jun 1, 1995·Free Radical Biology & Medicine·A P Breen, J A Murphy
Feb 1, 1995·Mutation Research·D W FairbairnK L O'Neill
Jan 1, 1995·Environmental and Molecular Mutagenesis·R PandrangiM Vrzoc
Mar 1, 1996·Nutrition Reviews·J M McCord
Jan 13, 2006·Ecotoxicology and Environmental Safety·Athanasios ValavanidisMichael Scoullos
Feb 19, 2008·Journal of Environmental Sciences (China)·Qiao-qiao ChiLangdon Alan
Jul 22, 2008·Mutation Research·D G S M CavalcanteS H Sofia
Oct 10, 2008·Environmental Monitoring and Assessment·W A RamsdorfM M Cestari
Jan 15, 2009·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Daoud AliW S Lakra
Jun 23, 2009·Environmental Monitoring and Assessment·George RejomonThresiamma Joseph
Feb 1, 1997·Toxicology in Vitro : an International Journal Published in Association with BIBRA·A DevauxG Monod
Jan 7, 2011·Environmental Monitoring and Assessment·Md Kawser AhmedMohammad Shahneawz Khan
Jan 26, 2011·Journal of Applied Toxicology : JAT·Shams Tabrez, Masood Ahmad
Oct 15, 2011·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Olga I KubrakVolodymyr I Lushchak
Nov 26, 2013·Pesticide Biochemistry and Physiology·G L PolettaM F Simoniello
May 20, 2014·Ecotoxicology and Environmental Safety·Amit Kumar GuptaMasood Ahmad

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Citations

Mar 19, 2016·Chemosphere·Cássio Resende MoraisEdimar Olegário Campos Júnior
Jul 6, 2016·Archives of Toxicology·M GleiW Schlörmann
Nov 7, 2016·Journal of Proteomics·André M AlmeidaPaulo Costa
May 2, 2020·Bulletin of Environmental Contamination and Toxicology·Seda Kontaş, Derya Bostancı
Jul 4, 2018·Biological Trace Element Research·Anton KovacikPeter Massanyi
Apr 28, 2019·Environmental Science and Pollution Research International·Farhana Ahmad Affandi, Mohd Yusoff Ishak
Oct 8, 2020·Scientific Reports·Mohd Shahnawaz KhanMd Irshad Ahmad
Dec 29, 2020·Heliyon·Letícia Sayuri ShiromaSonia Claudia Nascimento Queiroz
Oct 31, 2020·Environmental Geochemistry and Health·A YasothaT Sivakumar
May 19, 2021·Fish & Shellfish Immunology·Renata Antunes Estaiano de RezendeMarta Cristina Teixeira Duarte

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