PMID: 9429107Jan 16, 1998Paper

Bioactive glass fiber/polymeric composites bond to bone tissue

Journal of Biomedical Materials Research
M MarcolongoE Schepers

Abstract

Bioactive glass fibers were investigated for use as a fixation vehicle between a low modulus, polymeric composite and bone tissue. In an initial pilot study, bioactive glass fiber/polysulfone composites and all-polysulfone control rods were implanted into the rabbit tibia; the study was subsequently expanded with implantation into the rabbit femur. Bone tissue exhibited direct contact with the glass fibers and adjacent polymer matrix and displayed a mechanical bond between the composite and bone tissue after six weeks implantation. Interfacial bond strengths after six weeks implantation averaged 12.4 MPa, significantly higher than those of the all-polymer controls. Failure sites for the composite at six weeks generally occurred in the bone tissue or composite, whereas the failure site for the polymer implants occurred exclusively at the implant/tissue interface. The bioactive glass fiber/polysulfone composite achieved fixation to bone tissue through a triple mechanism: a bond to the bioactive glass fiber, mechanical interlocking between the tissue and glass fibers, and close apposition and possible chemical bond between the portions of the polymer and bone tissue. This last mechanism resulted from an overspill of bioactivity re...Continue Reading

References

Aug 1, 1992·Journal of Biomedical Materials Research·S D CookJ F Kay
May 1, 1992·The Journal of Bone and Joint Surgery. British Volume·G L MaistrelliA Binnington
Jan 1, 1991·The Journal of Bone and Joint Surgery. British Volume·G L MaistrelliI Harrington
Nov 1, 1989·Journal of Biomedical Materials Research·J Black
Dec 1, 1993·Biomaterials·K HayashiY Sugioka
Apr 1, 1993·Journal of Biomedical Materials Research·C C VerheyenP M Rozing
Nov 22, 1997·Journal of Biomedical Materials Research·M MarcolongoW C LaCourse
Jul 1, 1993·Journal of Applied Biomaterials : an Official Journal of the Society for Biomaterials·K KawanabeS Yoshihara

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Citations

Jul 13, 2002·Journal of Biomedical Materials Research·Kai ZhangLorraine F Francis
Jul 3, 2009·Journal of Materials Science. Materials in Medicine·Xiufeng XiaoXiaohong Ding
Feb 18, 2010·Journal of Materials Science. Materials in Medicine·Hanna TölliPekka Jalovaara
Dec 1, 2007·Pharmaceutical Research·Ann Leu, J Kent Leach
Nov 9, 2000·Biomaterials·M KellomäkiP Törmälä
Jul 2, 2003·Biomaterials·S Ladrón de Guevara-FernándezM Vallet-Regí
Nov 11, 2009·Nature Reviews. Rheumatology·Ericka M Bueno, Julie Glowacki
Aug 1, 2008·Journal of the Royal Society, Interface·M NavarroJ A Planell
May 13, 2005·Journal of Biomaterials Science. Polymer Edition·Garland FussellMichele Marcolongo
Feb 12, 2014·Journal of Materials Science. Materials in Medicine·Ruchi Mishra, Ashok Kumar
Mar 10, 2009·Acta Biomaterialia·R H MattilaP K Vallittu
May 8, 2009·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Ji-Hoon JoJun-Hyeog Jang
Mar 17, 2010·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Jessica J AlmHannu T Aro
Aug 15, 2015·Journal of Materials Science. Materials in Medicine·Kai ZhengAldo R Boccaccini
Oct 5, 2014·Materials Science & Engineering. C, Materials for Biological Applications·Shuqiong LiuXiufeng Xiao
Jun 12, 2016·Materials Science & Engineering. C, Materials for Biological Applications·Feven Mattews MichaelM Enamul Hoque
Aug 20, 2003·Journal of Biomedical Materials Research. Part a·Brian M HatcherAnthony B Brennan
Jun 19, 2001·Journal of Biomedical Materials Research·S N NazhatW Bonfield
Jul 25, 2007·Journal of Biomedical Materials Research. Part a·Emily HoMichele Marcolongo
Nov 1, 2018·Frontiers of Medicine·Bo LeiPeter X Ma
Apr 4, 2019·Advanced Healthcare Materials·Henri GranelYohann Wittrant
Jul 6, 2000·Journal of Biomedical Materials Research·C V Ragel, M Vallet-Regí
Jun 10, 2011·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Hailin ZhuJianyong Chen
Mar 15, 2015·Angewandte Chemie·Delia S Brauer
Jan 30, 2010·Biomacromolecules·Rodrigo OréficeAnthony Brennan

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