PMID: 15348113Sep 7, 2004Paper

Bioactive nanocrystalline sol-gel hydroxyapatite coatings

Journal of Materials Science. Materials in Medicine
C S Chai, B Ben-Nissan

Abstract

Sol-gel technology offers an alternative technique for producing bioactive surfaces for improved bone attachment. Previous work indicated that monophasic hydroxyapatite coatings were difficult to produce. In the present work hydroxyapatite was synthesized using the sol-gel technique with alkoxide precursors and the solution was allowed to age up to seven days prior to coating. It was found that, similar to the wet-chemical method of hydroxyapatite powder synthesis, an aging time is required to produce a pure hydroxyapatite phase. A methodology that has been successfully used to produce nanocrystalline hydroxyapatite thin film coatings via the sol-gel route on various substrates including alumina, Vycor glass, partially stabilized zirconia, Ti-6Al-4V alloy and single crystal MgO is described. Coatings produced on MgO substrates were characterized by X-ray diffraction and atomic force microscopy, while the analogous gels were examined with thermogravimetric and differential thermal analyses. The coatings were crack free and the surface was covered with small grains, of approximately 200 nm in size for samples fired to 1000 degrees C. Coating thickness varied between 70 and 1000 nm depending on the number of applied layers.

Citations

Nov 5, 2005·Journal of Biomedical Materials Research. Part a·Ping PengHans J Griesser
Aug 12, 2008·Biomedical Materials·Radha Gupta, Ashok Kumar
Apr 3, 2012·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Kate FoxNhiem Tran
Jan 11, 2003·Journal of Biomedical Materials Research. Part a·H SchliephakeC Hüttmann
Jul 19, 2005·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·I L DenryJ D Walters
Jul 18, 2012·Journal of Materials Science. Materials in Medicine·Nicolas VandecandelaereChristophe Drouet
Feb 26, 2003·Journal of Biomedical Materials Research. Part a·S RösslerH Worch
Nov 13, 2003·Journal of Biomedical Materials Research. Part a·Erik D Spoerke, Samuel I Stupp
Sep 28, 2012·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·D Alves CardosoS C G Leeuwenburgh
May 11, 2013·The International Journal of Artificial Organs·Sung-Hyun KimYoung-Kwon Seo
Sep 12, 2018·Langmuir : the ACS Journal of Surfaces and Colloids·Stéphanie SardaChristophe Drouet
Jul 1, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·R KumarK A Khor

❮ Previous
Next ❯

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.