Bioactive Properties of Syzygium cumini (L.) Skeels Pulp and Seed Phenolic Extracts

Frontiers in Microbiology
Catarina A SantosUelinton Manoel Pinto

Abstract

The emergence of bacterial strains resistant to different antibiotics has prompted the search for new sources of antimicrobial compounds. Studies have shown that jambolan [Syzygium cumini (L.) Skeels], a tropical fruit from the Mirtaceae family, contains a great variety of phytochemical compounds with high antioxidant and antimicrobial activity. This study aimed to determine the centesimal composition and physicochemical characteristics of the pulp and seed of S. cumini (L.) Skeels, as well as the content of total phenolic compounds and the antioxidant, antibacterial, antibiofilm and anti-quorum sensing (QS) activities of the phenolic extracts obtained from the pulp and the seeds of this fruit. The in vitro antibacterial and anti-QS activities of active films incorporating phenolic extracts were also evaluated. Additionally, we performed molecular docking of phenolic compounds present in jambolan with the CviR QS regulator of Chromobacterium violaceum. The composition and physicochemical characteristics of the samples presented similar values to those found for the species. However, the seed phenolic extract had a higher content of phenolic compounds and antioxidant activity than the pulp. Both phenolic extracts presented antib...Continue Reading

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Citations

Jun 3, 2021·Pharmaceutics·Giuliana DonadioFabrizio Dal Piaz
Oct 2, 2021·Frontiers in Microbiology·Catarina Angeli SantosUelinton Manoel Pinto

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Datasets Mentioned

BETA
SJRP00008916

Methods Mentioned

BETA
biosensor

Software Mentioned

Statistical Analysis System and Genetics
CLC Drug Discovery Workbench

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