Abstract
In this study, bioactive hydroxyapatite (HAP)-based bioceramics starting from cuttlefish bone powders have been prepared and characterized. In particular, fragmented cuttlefish bone was co-sintered with 30 wt% of Bioglass® -45S5 to synthesize HAP-based powders with enhanced mechanical properties and bioactivity. Commercial synthetic HAP was treated following the same procedure and used as a reference. The structure and composition of the bioceramics formulations were characterized using Fourier transform infrared spectroscopy, X-ray diffraction and scanning electron microscopy. After the thermal treatment of cuttlefish bone powder added with 30 wt% Bioglass, new phases with compositions of sodium calcium phosphate [Na3 Ca6 (PO4 )5 ], β-tricalcium phosphate [Ca3 (PO4 )] and amorphous silica were detected. In vitro cell culture studies were performed by evaluating proliferation, metabolic activity and differentiation of human osteoblast-like cells (MG63). Scaffolds made with cuttlefish bone powder exhibited increased apatite deposition, alkaline phosphatase activity and cell proliferation compared with commercial synthetic HAP. In addition, the ceramic compositions obtained after the combination with Bioglass® further enhanced th...Continue Reading
References
Nov 1, 1994·Bone·J Clover, M Gowen
Oct 1, 1994·Biomaterials·F H LinC M Lu
Dec 1, 1993·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·P D Delmas
Dec 30, 1999·Biomaterials·P Ducheyne, Q Qiu
Apr 18, 2003·Biomaterials·Min Wang
Jan 27, 2004·Biomaterials·S J KalitaA Bandyopadhyay
Jan 1, 1997·Journal of Materials Science. Materials in Medicine·I Rehman, W Bonfield
Sep 13, 2005·Bone·J H G RochaJ M F Ferreira
Oct 20, 2005·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Hideki Yoshikawa, Akira Myoui
May 8, 2007·Advanced Drug Delivery Reviews·Patrícia B MalafayaRui L Reis
Aug 9, 2007·Acta Biomaterialia·Kenneth S VecchioCholl W Kim
Jun 23, 2010·Journal of Materials Science. Materials in Medicine·H IvankovicZ Schauperl
Aug 27, 2010·Journal of Tissue Engineering and Regenerative Medicine·J T Oliveira, R L Reis
Feb 5, 2011·Biomaterials·Alexander HoppeAldo R Boccaccini
Mar 2, 2011·Acta Biomaterialia·Juliana T Y LeeXiong Lu
Mar 29, 2011·Acta Biomaterialia·Hongjian Zhou, Jaebeom Lee
Mar 27, 2012·Journal of Biomedical Materials Research. Part a·Beom-Su KimJun Lee
Mar 19, 2014·Journal of Orthopaedic Surgery and Research·Ahmad OryanNicola Maffulli
Mar 19, 2014·Biopolymers·Sayani Chattopadhyay, Ronald T Raines
Jul 27, 2014·Materials Science & Engineering. C, Materials for Biological Applications·Emilija TkalčecHrvoje Ivanković
Jan 30, 2015·Journal of Tissue Engineering and Regenerative Medicine·Judith SewingHolger Notbohm
Jan 1, 2014·Bone Research·Ping WangHockin H K Xu
Mar 15, 2016·International Journal of Biological Macromolecules·Natascia CozzaClaudio Migliaresi
Jul 6, 2010·Materials·Lutz-Christian Gerhardt, Aldo R Boccaccini
Jan 30, 2010·Materials Science & Engineering. C, Materials for Biological Applications·Hande DemirkiranPranesh Aswath
Citations
Aug 31, 2020·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Xiao ZhengQingqing Yao
Feb 6, 2019·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·W-J ChenT-Y Tsai
Mar 3, 2020·Beilstein Journal of Nanotechnology·Satheeshkumar BaluJaison Jeevanandam
Jun 30, 2018·Materials·Valentina MitranAnisoara Cimpean
Dec 20, 2020·Dental Materials : Official Publication of the Academy of Dental Materials·Yiping LiXiaojing Chen
Jan 28, 2021·Nanomaterials·Francesca CestariVincenzo M Sglavo
May 18, 2021·Bioactive Materials·Mei-Chen WanLi-Na Niu