PMID: 20644594Jul 21, 2010Paper

Bioactivity of aviprin and aviprin-3''-O-glucoside, two linear furanocoumarins from Apiaceae

Bioorganicheskaia khimiia
Seyed Mehdi Razavi, Gholamreza Zarrini

Abstract

Furanocoumarins are well-known natural products that occur in the most evolved genera of Apiaceae family. This compounds were found to have cytotoxic, phytotoxic, photosensitizing, insecticidal, antibacterial and high anti-fungal effects. Aviprin is considered as a linear furanocoumarin substituted at C8 with an oxygenated prenyl residue. In this study we found that aviprin is a bioactive compound that exhibits high antibacterial, antifungal and phytotoxic activity. The compound stunted the germination of lettuce seeds with IC50 value of 0.270 mg/mL. The compound also inhibited the mycelia growth of Sclerotinia sclerotiorum. Aviprin indicated antibacterial activity against tested gram negative and positive bacteria with inhibition zone of 19-23.5 mm. Our results shown that aviprin can play an allelopatic role for plant.

Citations

Sep 6, 2013·Journal of Industrial Microbiology & Biotechnology·Nguyen Huy Thuan, Jae Kyung Sohng
Mar 19, 2016·Natural Product Research·Seyed Mehdi RazaviSatyajit Dey Sarker
Aug 24, 2013·Bioorganicheskaia khimiia·Seyed Mehdi RazaviGholamreza Zarrini
Aug 27, 2021·Evidence-based Complementary and Alternative Medicine : ECAM·Seyyed Mojtaba MousaviNelson Pynadathu Rumjit

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