Bioadsorption strategies with yeast molecular display technology

Biocontrol Science
Seiji Shibasaki, Mitsuyoshi Ueda

Abstract

Molecular display techniques using microbial cell surfaces have been widely developed in the past twenty years, and are useful tools as whole cell catalysts for various applications such as bioconversion, bioremediation, biosensing, and the screening system of protein libraries. Furthermore, different types of microbial cells among eukaryotic and prokaryotic strains have been investigated for their use in surface display technologies. Recently, several kinds of protein-displaying yeasts have been utilized as bioadsorbents in this platform technology. In particular, these trials have successfully expanded the possibility of applications to metal binding, affinity purification, and receptor-ligand interaction by using the yeast cell surface. In this mini review, we describe the general principles of molecular display technology using yeast cells and its applications, with a particular focus on bioadsorption.

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Citations

Jan 11, 2020·Applied Microbiology and Biotechnology·Qinghui YuGuoquan Hu
Feb 13, 2018·Applied Microbiology and Biotechnology·Cecilia Andreu, Marcel Lí Del Olmo
Jan 4, 2021·Bioprocess and Biosystems Engineering·Mengqi YeGuanjun Chen
Aug 11, 2021·The Journal of General and Applied Microbiology·Kohei KatsuradaKatsumi Takayama

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