Bioavailability of bound pesticide residues and potential toxicologic consequences - an update

Proceedings of the Society for Experimental Biology and Medicine
S KacewS U Khan

Abstract

The growing demand for enhanced food productivity to meet the needs of the global population has led farmers to use sophisticated agricultural technology in which pesticides play a crucial role. Pesticide use has a positive and dramatic impact on agricultural production through protection of crops against insects, pests, and disease, but every effort must be made to ensure that application is safe and, more importantly, to assure safety for human and environmental health. Since our initial review (1), global usage of pesticides has increased and knowledge regarding the biological significance of bound pesticide residues has expanded. The fact that more reports are appearing in the literature signifies an increased awareness of the presence of bound pesticide residues and indicates that a greater number of scientists are attempting to establish the potential toxicologic consequences of this pesticides residue fraction. Rico (2), in a review in 1990, concluded that covalently bound residues in edible animal tissues were not carcinogenic, were not readily bioavailable, and hence produced little, if any, adverse effects. Whether this conclusion is applicable to the presence and consequences of bound pesticide residues in plants and...Continue Reading

Citations

Jan 27, 2012·Journal of Agricultural and Food Chemistry·Sophie Pascal-LorberFrançois Laurent
Oct 21, 2020·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Marc H G BerntssenMarco J Zeilmaker
Sep 20, 2000·Journal of Agricultural and Food Chemistry·F Laurent, R Scalla

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