Oct 20, 2006

Bioavailability of trace metals to aquatic microorganisms: importance of chemical, biological and physical processes on biouptake

Biochimie
Isabelle WormsKevin J Wilkinson

Abstract

An important challenge in environmental biogeochemistry is the determination of the bioavailability of toxic and essential trace compounds in natural media. For trace metals, it is now clear that chemical speciation must be taken into account when predicting bioavailability. Over the past 20 years, equilibrium models (free ion activity model (FIAM), biotic ligand model (BLM)) have been increasingly developed to describe metal bioavailability in environmental systems, despite the fact that environmental systems are always dynamic and rarely at equilibrium. In these simple (relatively successful) models, any reduction in the available, reactive species of the metal due to competition, complexation or other reactions will reduce metal bioaccumulation and thus biological effects. Recently, it has become clear that biological, physical and chemical reactions occurring in the immediate proximity of the biological surface also play an important role in controlling trace metal bioavailability through shifts in the limiting biouptake fluxes. Indeed, for microorganisms, examples of biological (transport across membrane), chemical (dissociation kinetics of metal complexes) and physical (diffusion) limitation can be demonstrated. Furthermo...Continue Reading

  • References64
  • Citations55

References

Mentioned in this Paper

Microorganism
Biological Membrane
Biochemical Pathway
Organic acids, Gynecological
Oxalate
Extracellular
Enzymes, antithrombotic
Adenosine Triphosphatases
Amino Acids, I.V. solution additive
Complex (molecular entity)

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